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减肥手术后代谢因子的稳定性。

Stability of Metabolic Factor Before and After Bariatric Surgery.

作者信息

Davis Brandon, Indelicato Joseph

机构信息

Davis Psychological Services, PC, 821 5th Ave, Suite 201, Grinnell, IA, USA.

出版信息

Obes Surg. 2016 Oct;26(10):2379-83. doi: 10.1007/s11695-016-2111-6.

DOI:10.1007/s11695-016-2111-6
PMID:26922185
Abstract

BACKGROUND

A new metric called metabolic factor (resting metabolic rate/weight) has previously been established that can differentiate between people who are obese, overweight, and of normal weight. Previous studies were re-analyzed and found that people who lost weight did not experience a change in their metabolic factor.

MATERIALS AND METHODS

The current study measured the metabolic factor of 18 individuals before and after bariatric surgery.

RESULTS

As expected, individuals lost nearly 100 lb and therefore lowered their resting metabolic rate from 2614.3 to 1954.4 kcal (p < 0.05). However, the pre-operative metabolic factor of 8.1 (1.1) cal/lb did not change significantly as it slightly increased to 8.6 (0.88) after surgery (p = 0.19). Weight loss was not statistically significantly correlated with change in metabolic factor (r = 0.22). The follow-up metabolic factor negatively correlated with post-operative BMI, r = -0.48 (p < 0.05), indicating the higher the metabolic factor, the lower the post-operative BMI.

CONCLUSIONS

This study seems to establish the possibility that metabolic factor is not simply a function of one's current weight, but instead might be a stable characteristic unique to each individual.

摘要

背景

先前已建立一种名为代谢因子(静息代谢率/体重)的新指标,它能够区分肥胖、超重和体重正常的人群。对先前的研究进行重新分析后发现,体重减轻的人其代谢因子并未发生变化。

材料与方法

本研究测量了18名个体在接受减肥手术前后的代谢因子。

结果

正如预期的那样,个体体重减轻了近100磅,因此静息代谢率从2614.3千卡降至1954.4千卡(p < 0.05)。然而,术前代谢因子为8.1(1.1)卡/磅,术后略有增加至8.6(0.88),但未发生显著变化(p = 0.19)。体重减轻与代谢因子的变化在统计学上无显著相关性(r = 0.22)。随访时的代谢因子与术后BMI呈负相关,r = -0.48(p < 0.05),表明代谢因子越高,术后BMI越低。

结论

本研究似乎证实了代谢因子并非仅仅是一个人当前体重的函数,而是可能是每个人独有的稳定特征。

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Metabolic and nutritional status changes after 10% weight loss in severely obese patients treated with laparoscopic surgery vs integrated medical treatment.腹腔镜手术与综合内科治疗的重度肥胖患者体重减轻10%后的代谢和营养状况变化
Obes Surg. 2007 Dec;17(12):1592-8. doi: 10.1007/s11695-007-9286-9. Epub 2007 Nov 14.
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