Universidad Autónoma Metropolitana, Unidad Xochimilco, UAM, Mexico City, Mexico.
Int J Oral Maxillofac Surg. 2012 May;41(5):569-75. doi: 10.1016/j.ijom.2012.02.002. Epub 2012 Mar 6.
Adult head and neck soft tissue sarcomas are rare and display a variety of histological types and clinical characteristics; they are also associated with a variety of mortality risks. The purpose of this study was to examine all patients treated at the Instituto Nacional de Cancerologia for head and neck sarcoma during a 5-year period. Fifty-one adult patients were examined and treated for head and neck sarcomas from 2004 to 2009. The 51 tumours were histologically re-evaluated by expert pathologists and classified as low, intermediate or high grade sarcomas. A multivariate analysis was performed to evaluate the surgical margins, histological grades, and clinical stages as prognostic factors for the disease. Adult head and neck soft tissue tumours are rare, and they are associated with poor prognosis for patients, especially at clinical stages III and IV. The average survival rate after 2 years is 45%, and most of these patients die because of disease progression and metastases.
成人头颈部软组织肉瘤罕见，具有多种组织学类型和临床特征，且与多种死亡风险相关。本研究旨在研究 2004 年至 2009 年期间在国立癌症研究所接受治疗的所有头颈部肉瘤患者。共检查和治疗了 51 例成人头颈部肉瘤患者。由专家病理学家对头颈部的 51 个肿瘤进行了重新评估，并将其分类为低级别、中级别或高级别肉瘤。进行了多变量分析，以评估手术切缘、组织学分级和临床分期作为疾病的预后因素。成人头颈部软组织肿瘤罕见，且患者预后不良，尤其是在 III 期和 IV 期。2 年后的平均生存率为 45%，大多数患者因疾病进展和转移而死亡。
