Liuzzi Juan Francisco, Da Cunha Maribel, Salas Daniuska, Siso Saul, Garriga Esteban
Head and Neck Department, Hospital Oncology Service, Venezuelan Institute of Social Security, Caracas 1040, Venezuela.
Head and Neck Cancer Surgery, Hospital Oncology Service, Venezuelan Institute of Social Security, Caracas 1040, Venezuela.
Ecancermedicalscience. 2017 Jun 2;11:740. doi: 10.3332/ecancer.2017.740. eCollection 2017.
Sarcomas are infrequent and heterogeneous tumours. They represent 1-2% of all malignant neoplasms in adults and between 4% and 10% of head and neck cancers.
The research was retrospective, descriptive, and cross-sectional.
A study population of 62 patients with a mean age of 44 years was obtained; the most frequent location was the soft tissues of the neck (25.3%) and the mean tumour size was 7.1 cm; the most frequent diagnosis was undifferentiated pleomorphic sarcoma (25.5%) and the majority were stage III (41.4%). The lowest survival rates were associated with T2a and T2b tumours ( = 0.014), the presence of lymph node metastasis ( = 0.001), advanced stages ( = 0.003), and invasion of bone, blood vessels and/or nerves ( = 0.008).
Late diagnosis is the main factor associated with decreased survival in patients with head and neck sarcomas.
肉瘤是罕见且异质性的肿瘤。它们占成人所有恶性肿瘤的1%-2%，占头颈癌的4%-10%。
本研究为回顾性、描述性横断面研究。
获得了一个由62例患者组成的研究群体，平均年龄44岁；最常见的部位是颈部软组织（25.3%），平均肿瘤大小为7.1厘米；最常见的诊断是未分化多形性肉瘤（25.5%），大多数为III期（41.4%）。最低生存率与T2a和T2b肿瘤（P = 0.014）、存在淋巴结转移（P = 0.001）、晚期（P = 0.003）以及侵犯骨骼、血管和/或神经（P = 0.008）相关。
诊断延迟是头颈肉瘤患者生存率降低的主要相关因素。
