Horimoto N, Koyanagi T, Satoh S, Yoshizato T, Nakano H
Department of Gynecology and Obstetrics, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Am J Obstet Gynecol. 1990 Nov;163(5 Pt 1):1480-4. doi: 10.1016/0002-9378(90)90609-b.
The goal of this study was to determine whether rapid eye movement and slow eye movement exist during the eye-movement period in the human fetus in utero. We studied 21 fetuses with real-time ultrasonography, 10 from 33 to 36 weeks and 11 from 37 to 41 weeks' gestation. We used the duration of eye-movement unit as a parameter and calculated the cumulative duration from the shortest to a given duration of eye movement per individual case. A scattergram of cumulative duration versus given duration obtained from all cases in each age group was analyzed with piecewise linear regression to search for a critical point(s). Critical given duration points were noted and reached statistical significance at 0.62 second and at 0.76 second during 33 to 36 and 37 to 40 weeks of gestation, respectively. These findings reveal two different types of eye movement: one with a duration of less than 0.6 to 0.8 second and the other with a duration of greater than 0.6 to 0.8 second. These findings are compatible with previous criteria on rapid and slow eye movements, respectively, at 33 weeks of gestation onward. The mean value of cumulative duration at the critical point increased from 29.0% between 33 and 36 weeks to 47.1% between 37 and 41 weeks of gestation, indicating an increase in the proportionate amount of time maintaining rapid eye movement as gestation advances.
本研究的目的是确定子宫内人类胎儿眼动期是否存在快速眼动和慢速眼动。我们使用实时超声对21例胎儿进行了研究，其中10例妊娠33至36周，11例妊娠37至41周。我们将眼动单元的持续时间作为参数，并计算每个个体病例从最短到给定眼动持续时间的累积持续时间。对每个年龄组所有病例获得的累积持续时间与给定持续时间的散点图进行分段线性回归分析，以寻找临界点。在妊娠33至36周和37至40周期间，临界给定持续时间点分别为0.62秒和0.76秒，具有统计学意义。这些发现揭示了两种不同类型的眼动：一种持续时间小于0.6至0.8秒，另一种持续时间大于0.6至0.8秒。这些发现分别与妊娠33周及以后关于快速和慢速眼动的先前标准相符。临界点处累积持续时间的平均值从妊娠33至36周的29.0%增加到妊娠37至41周的47.1%，表明随着妊娠进展，维持快速眼动的时间比例增加。
