Department of Surgery, University of Minnesota, Minneapolis, MN, USA.
Ann Surg Oncol. 2012 Aug;19(8):2607-11. doi: 10.1245/s10434-012-2304-8. Epub 2012 Mar 9.
Tumescence is the injection of local anesthetic and crystalloid into the subcutaneous tissue to establish a bloodless plane for surgical dissection. The aim of our study was to evaluate outcomes after mastectomy with tumescent technique compared to electrocautery dissection.
We conducted a single-institution retrospective evaluation of patients who underwent mastectomy between 2007 and 2011. The tumescent technique was performed by injecting 1% lidocaine with epinephrine mixed in a 10% ratio with lactated Ringer solution into the mastectomy flaps followed by sharp dissection. Significance testing was done to evaluate for outcome differences between the two surgical groups.
Among the 134 patients, 64 underwent electrocautery and 70 underwent tumescent-assisted dissection. The overall complication rate was 21.6% (tumescent, 20.0%; electrocautery, 23.4%, P = 0.63). Flap necrosis requiring operative debridement was the most common complication in the tumescent group (n = 6). On multivariate analysis, tumescent technique was not associated with an increased complication rate. Immediate reconstruction was the only factor that increased the risk of complication (odds ratio 12.95, P < 0.001).
The tumescence surgery technique should be utilized with caution in patients undergoing immediate reconstruction, as a trend for higher complication rates was observed in these cases, and flap viability is particularly important in this setting. Future prospective studies are needed to further evaluate blood loss, operative time, postoperative pain, and duration of drainage catheters after tumescent mastectomy technique.
肿胀技术是将局部麻醉剂和晶体溶液注入皮下组织,以建立用于手术解剖的无血平面。我们的研究目的是评估肿胀技术与电刀解剖相比在乳房切除术的结果。
我们对 2007 年至 2011 年间接受乳房切除术的患者进行了单机构回顾性评估。肿胀技术是通过将 1%利多卡因与肾上腺素以 10%的比例混合在乳酸林格溶液中注入乳房切除术皮瓣中,然后进行锐性解剖来完成的。通过进行显著性检验来评估两种手术组之间的结果差异。
在 134 例患者中,64 例行电刀,70 例行肿胀辅助解剖。总的并发症发生率为 21.6%(肿胀组 20.0%;电刀组 23.4%,P = 0.63)。肿胀组最常见的并发症是皮瓣坏死需要手术清创(n = 6)。多变量分析显示,肿胀技术与并发症发生率增加无关。即刻重建是唯一增加并发症风险的因素(优势比 12.95,P < 0.001)。
在接受即刻重建的患者中应谨慎使用肿胀手术技术,因为在这些情况下观察到并发症发生率较高的趋势,并且在这种情况下皮瓣的存活能力尤为重要。需要进一步进行前瞻性研究来评估肿胀乳房切除术技术后的出血量、手术时间、术后疼痛和引流导管持续时间。