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用于治疗糖尿病患者足部和腿部难愈合溃疡的中厚皮片移植:一项回顾性研究。

Split thickness skin grafts for the treatment of non-healing foot and leg ulcers in patients with diabetes: a retrospective review.

作者信息

Anderson John J, Wallin Kelly J, Spencer Loren

机构信息

Alamogordo Orthopedics and Sports Medicine, Alamogordo, New Mexico, USA.

出版信息

Diabet Foot Ankle. 2012;3. doi: 10.3402/dfa.v3i0.10204. Epub 2012 Feb 20.

Abstract

We retrospectively reviewed 107 diabetic patients who received a split thickness skin graft (STSG) for treatment of a non-healing diabetic foot or leg ulcer to describe healing times based on patient characteristics, comorbidities or complications. The minimum follow-up was 6 months from the time of STSG application. The mean time to healing among all patients was 5.1 weeks (3 to 16 weeks). The mean healing time for patients with complications was 12.0 weeks (10 to 16 weeks) while the mean healing time for those without complications was 4.9 weeks (3 to 10 weeks). Overall complication rate was 2.8%. Patients with a STSG take of less than 95% had a mean healing time of 7.9 weeks compared to 4.8 weeks for those with a STSG take of 100% (p<0.001). The use of autologous STSG for treatment of non-healing diabetic foot and leg wounds is a viable method for soft tissue closure and may present a low complication rate and a satisfactory rate of healing.

摘要

我们回顾性分析了107例接受中厚皮片移植(STSG)治疗不愈合糖尿病足或腿部溃疡的糖尿病患者,以根据患者特征、合并症或并发症描述愈合时间。自应用STSG起,最短随访时间为6个月。所有患者的平均愈合时间为5.1周(3至16周)。有并发症患者的平均愈合时间为12.0周(10至16周),而无并发症患者的平均愈合时间为4.9周(3至10周)。总体并发症发生率为2.8%。STSG成活率低于95%的患者平均愈合时间为7.9周,而STSG成活率为100%的患者平均愈合时间为4.8周(p<0.001)。使用自体STSG治疗不愈合糖尿病足和腿部伤口是一种可行的软组织闭合方法,并发症发生率可能较低,愈合率令人满意。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2918/3297411/a69adf4dfd0d/DFA-3-10204-g001.jpg

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