Department Early Psychosis, Academic Medical Centre, University of Amsterdam Private Practice, Amsterdam, The Netherlands.
Early Interv Psychiatry. 2013 Feb;7(1):64-70. doi: 10.1111/j.1751-7893.2012.00356.x. Epub 2012 Mar 9.
Recently, a mindfulness therapy for people with psychotic disorders was developed. However, clinicians and researchers are cautious given case reports in which extensive meditation provoked psychotic symptoms in people with a psychotic disorder. The purpose of this study was to examine the feasibility, adverse effects and possible favourable effects of mindfulness-based therapy (MBT) in people recently recovering from a first episode of psychosis.
A nonrandomized, non-controlled prospective follow-up study. Patients were offered an MBT that consisted of eight 1-hour sessions within a 4-week time span. Positive and Negative Syndrome Scale, Symptoms Checklist 90 and the Southampton Mindfulness Questionnaire were assessed before and after the therapy.
Of the 16 persons who started MBT, 13 completed (81.5%) the therapy. No significant increase in psychotic symptoms was found. Between two meetings, one participant initially misunderstood the mindfulness instructions, which led to an increase in distress. No increased awareness of intrusive thoughts or visual or auditory hallucinations was reported by participants. We found a decrease in agoraphobic symptoms (p < 0.028) and in psychoneuroticism (P < 0.025).
The MBT had no significant adverse effect on psychotic symptoms in patients in this small pilot study, neither did it raise the level of mindfulness in the participants. A decrease in psychological symptoms was found, although one patient experienced an increase in symptoms of distress. Our study demonstrates that therapists should be cautious that therapy and practice instructions are understood properly. Future studies are feasible and needed, in larger samples with an RCT design, in order to draw conclusions regarding the effects of the MBT.
最近,针对精神病患者开发了一种正念疗法。然而,鉴于有病例报告称,广泛的冥想会在精神病患者中引发精神病症状,临床医生和研究人员对此持谨慎态度。本研究的目的是检验正念疗法(MBT)在刚刚经历首发精神病的患者中的可行性、不良反应和可能的有益效果。
一项非随机、非对照的前瞻性随访研究。为患者提供为期 4 周、每周 1 次、每次 1 小时的 8 次 MBT。在治疗前后,分别使用阳性和阴性症状量表、症状清单 90 和南安普顿正念问卷进行评估。
16 名开始接受 MBT 的患者中,有 13 名(81.5%)完成了治疗。未发现精神病症状明显增加。在两次会议之间,有 1 名参与者最初误解了正念指导,导致痛苦增加。参与者没有报告对侵入性思维或视觉或听觉幻觉的意识增强。我们发现广场恐怖症症状(p < 0.028)和精神神经症(P < 0.025)减少。
在这项小型试点研究中,MBT 对患者的精神病症状没有明显的不良影响,也没有提高参与者的正念水平。虽然有 1 名患者的痛苦症状增加,但我们发现心理症状有所减轻。我们的研究表明,治疗师应该谨慎确保治疗和实践指导得到正确理解。未来的研究是可行的,需要在更大的样本中进行 RCT 设计,以得出关于 MBT 效果的结论。