School of Materials Science and Engineering, University of New South Wales, NSW 2052, Australia.
Acta Biomater. 2012 Jul;8(6):2375-83. doi: 10.1016/j.actbio.2012.03.009. Epub 2012 Mar 9.
A series of six unique Ca-based bulk metallic glasses were synthesized and characterized. The glasses were designed to consist solely of the biocompatible elements Ca, Mg and Zn, with the view to their potential use as bioresorbable metals for orthopaedic applications. The alloys had a critical casting thickness of up to 4.5 mm. Mechanical and thermophysical testing revealed a Young's modulus (stiffness) of ∼40 GPa. Glass transition temperatures ranged from 119 to 129°C, above which the alloys can be formed like a thermoplastic polymer. In vitro biocorrosion testing using a combination of polarization and mass loss techniques revealed that the corrosion rate of these alloys is relatively rapid, although, in some cases, it may be tailored through alloy composition.
合成并表征了一系列六种独特的基于 Ca 的大块金属玻璃。这些玻璃仅由生物相容性元素 Ca、Mg 和 Zn 组成，旨在用作骨科应用的可生物吸收金属。这些合金的临界铸造厚度高达 4.5 毫米。力学和热物理测试显示杨氏模量（刚度）约为 40 GPa。玻璃化转变温度范围为 119 至 129°C，高于该温度，合金可以像热塑性聚合物一样成型。使用极化和质量损失技术的组合进行的体外生物腐蚀性测试表明，这些合金的腐蚀速率相对较快，尽管在某些情况下，通过合金成分可以对其进行调整。
