Bhawan J, Edelstein L
J Cutan Pathol. 1977 Dec;4(6):300-7. doi: 10.1111/j.1600-0560.1977.tb00921.x.
Angiofibromas from two patients with tuberous sclerosis were studied by light and electron microscopy. Light microscopy revealed that these tumor-like nodules (which in the past have been called adenoma sebaceum) were made up of dilated capillaries, venules and arterioles embedded in connective tissue. At the ultrastructural level the arterioles embedded in connective tissue. At the ultrastructural level the endothelium of these vessels showed large numbers of microvilli on their luminal surface. The stroma contained many banded structures (so-called fibrous long spacing collagen). Myofibroblasts recently described in juvenile nasopharyngeal angiofibromas were not found in these angiofibromas of tuberous sclerosis.
对两名结节性硬化症患者的血管纤维瘤进行了光镜和电镜研究。光镜显示,这些肿瘤样结节(过去称为皮脂腺瘤)由嵌入结缔组织中的扩张毛细血管、小静脉和小动脉组成。在超微结构水平上,结缔组织中的小动脉……在超微结构水平上,这些血管的内皮在管腔表面有大量微绒毛。基质中含有许多带状结构(所谓的纤维长间距胶原)。在结节性硬化症的这些血管纤维瘤中未发现最近在青少年鼻咽血管纤维瘤中描述的肌成纤维细胞。