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足部皮肤干燥症:两种保湿剂效果的比较研究

Xerosis of the feet: a comparative study on the effectiveness of two moisturizers.

作者信息

Baalham Paul, Birch Ivan, Young Maria, Beale Clare

出版信息

Br J Community Nurs. 2011 Dec;16(12):591-2, 594-7. doi: 10.12968/bjcn.2011.16.12.591.

DOI:10.12968/bjcn.2011.16.12.591
PMID:22413404
Abstract

The treatment for xerosis (dry skin) is the repeated use of moisturizers to hydrate the skin. Their use is based on sound evidence of the importance of maintaining the skin's water content. Although the skin on the plantar surface of the foot is very thick, it is highly visco-elastic and copes with high levels of frictional, compressive and shear stresses applied to it by being supple and well hydrated. Problems arise when the skin becomes dry and loses its elastic properties. Fissures can occur which are often painful and can act as portals for infection. This article describes a double-blind clinical study to evaluate and compare the effectiveness of two commonly used moisturizers and to see if one was significantly better than the other at hydrating the skin of the feet. The two creams used were Aqueous Cream BP and CCS Foot Care Cream. Skin hydration levels were measured before any application of moisturizer and again after two weeks of twice daily application. Results showed that the regular use of both moisturizers had a significant hydrating effect on the skin. However, CCS Foot Care Cream had a significantly greater hydrating effect than Aqueous Cream BP.

摘要

干性皮肤(皮肤干燥症)的治疗方法是反复使用保湿剂来为皮肤补水。保湿剂的使用基于维持皮肤含水量重要性的确凿证据。尽管脚底的皮肤非常厚,但它具有高度的粘弹性,通过保持柔软和充分水润来应对施加于其上的高水平摩擦、压缩和剪切应力。当皮肤变得干燥并失去其弹性特性时,问题就会出现。可能会出现裂缝,这些裂缝通常很疼,并且可能成为感染的入口。本文描述了一项双盲临床研究,以评估和比较两种常用保湿剂的有效性,并查看其中一种在为足部皮肤补水方面是否明显优于另一种。所使用的两种乳膏分别是英国药典水性乳膏和CCS足部护理乳膏。在涂抹任何保湿剂之前以及每天涂抹两次、持续两周之后,分别测量皮肤的水合水平。结果表明,经常使用这两种保湿剂对皮肤都有显著的补水效果。然而,CCS足部护理乳膏的补水效果明显优于英国药典水性乳膏。

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1
Xerosis of the feet: a comparative study on the effectiveness of two moisturizers.足部皮肤干燥症:两种保湿剂效果的比较研究
Br J Community Nurs. 2011 Dec;16(12):591-2, 594-7. doi: 10.12968/bjcn.2011.16.12.591.
2
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An urea, arginine and carnosine based cream (Ureadin Rx Db ISDIN) shows greater efficacy in the treatment of severe xerosis of the feet in Type 2 diabetic patients in comparison with glycerol-based emollient cream. A randomized, assessor-blinded, controlled trial.一种基于尿素、精氨酸和肌肽的乳膏(Ureadin Rx Db ISDIN)与基于甘油的润肤霜相比,在治疗2型糖尿病患者足部严重干燥症方面显示出更高的疗效。一项随机、评估者盲法、对照试验。
BMC Dermatol. 2012 Sep 25;12:16. doi: 10.1186/1471-5945-12-16.

引用本文的文献

1
Moisturisers for the treatment of foot xerosis: a systematic review.治疗足部干燥症的保湿剂:系统评价。
J Foot Ankle Res. 2017 Feb 7;10:9. doi: 10.1186/s13047-017-0190-9. eCollection 2017.
2
An urea, arginine and carnosine based cream (Ureadin Rx Db ISDIN) shows greater efficacy in the treatment of severe xerosis of the feet in Type 2 diabetic patients in comparison with glycerol-based emollient cream. A randomized, assessor-blinded, controlled trial.一种基于尿素、精氨酸和肌肽的乳膏(Ureadin Rx Db ISDIN)与基于甘油的润肤霜相比,在治疗2型糖尿病患者足部严重干燥症方面显示出更高的疗效。一项随机、评估者盲法、对照试验。
BMC Dermatol. 2012 Sep 25;12:16. doi: 10.1186/1471-5945-12-16.