Ohtsuka T, Lee H C, Yamaguchi M, Mori N
Department of Obstetrics and Gynecology, Miyazaki Medical College, Japan.
Br J Obstet Gynaecol. 1990 Sep;97(9):843-6. doi: 10.1111/j.1471-0528.1990.tb02581.x.
The effect of dipalmitoylphosphatidylcholine (DPPC, L-alpha-lecithin), a substance not containing arachidonic acid, on prostaglandin E (PGE) production of amniotic membrane was studied. DPPC (3.125-800 micrograms/ml) stimulated PGE production of amniotic membrane (150-200%), suggesting that lecithin, the major surfactant component, is directly involved in the mechanism of human parturition as a stimulator of PGE production.
研究了一种不含花生四烯酸的物质二棕榈酰磷脂酰胆碱(DPPC,L-α-卵磷脂)对羊膜前列腺素E(PGE)产生的影响。DPPC(3.125 - 800微克/毫升)刺激羊膜PGE产生(150 - 200%),这表明作为主要表面活性剂成分的卵磷脂作为PGE产生的刺激物直接参与了人类分娩机制。