Department of Gastroenterology and Hepatology, Academic Medical Center Amsterdam, Amsterdam, The Netherlands.
Aliment Pharmacol Ther. 2012 May;35(9):1073-9. doi: 10.1111/j.1365-2036.2012.05070.x. Epub 2012 Mar 20.
Patients with gastro-oesophageal reflux disease (GERD) frequently report excessive belching but it is not known what determines the severity of these complaints.
To determine what causes troublesome belching symptoms in GERD patients.
We included 90 consecutive patients who were referred for ambulatory 24-h pH-impedance measurement as part of the analysis of reflux symptoms. Overall severity of belching was reported by the patients using a 3-point scale. Furthermore, each belch perceived during the ambulatory measurement was reported by the patients using a symptom diary.
No significant differences in frequency of gastric belches or combined liquid reflux and gastric belches were observed. However, the number of supragastric belches was significantly higher in patients with severe belching complaints compared to patients with moderate and none to mild complaints. Moreover, the number of supragastric belches which coincided with a liquid reflux episode was significantly higher in patients with severe complaints than in those with moderate and none to mild complaints. Per-patient analysis showed that belches coinciding with a liquid reflux event were more often symptomatic than isolated belches.
The type of belch determines the burden of belching complaints in patients with GERD. Supragastric belches, not gastric belches determine the severity of belching complaints.
胃食管反流病（GERD）患者常报告过度嗳气，但尚不清楚是什么决定了这些症状的严重程度。
确定 GERD 患者嗳气症状严重的原因。
我们纳入了 90 例连续患者，他们因反流症状分析而接受了门诊 24 小时 pH 阻抗测量。患者使用 3 分制报告整体嗳气严重程度。此外，患者使用症状日记报告在门诊测量期间感知到的每一次嗳气。
未观察到胃嗳气或混合液体反流和胃嗳气的频率存在显著差异。然而，与中度和无至轻度嗳气抱怨的患者相比，严重嗳气抱怨的患者的胃上部嗳气次数明显更高。此外，严重嗳气抱怨的患者与中度和无至轻度嗳气抱怨的患者相比，与液体反流事件同时发生的胃上部嗳气次数明显更高。每位患者的分析表明，与液体反流事件同时发生的嗳气比孤立的嗳气更常出现症状。
嗳气的类型决定了 GERD 患者嗳气抱怨的负担。胃上部嗳气而不是胃嗳气决定了嗳气抱怨的严重程度。
