University of Western Australia, Western Australian Institute for Medical Research, Nedlands, WA, Australia.
Int Arch Occup Environ Health. 2013 Apr;86(3):261-9. doi: 10.1007/s00420-012-0761-9. Epub 2012 Mar 21.
To reduce the socio-economic burden of persistent low back pain (LBP), factors influencing the progression of acute/subacute LBP to the persistent state must be identified at an early stage.
Prospective inception cohort study of patients attending a health practitioner for their first episode of acute/subacute or recurrent LBP. Patients were assessed at baseline addressing occupational, psychological, biomedical and demographic/lifestyle factors and followed up over 6 months. Multivariate logistic regression analysis was performed separately for the variables groups of the four different domains, controlling for age, gender and body mass index. The overall predictive value was calculated for the full regression models of the different domains. Finally, all significant variables from the different domains were combined into a final predictor model.
The final four-predictor model predicted 51 % of variance of persistent LBP and included 'resigned attitude towards the job' (OR 1.73; 95 % CI 1.16-2.59), 'social support at work' (OR 0.54; 95 % CI 0.32-0.90), 'functional limitation' (OR 1.05; 95 % CI 1.01-1.10) and 'duration of LBP' (OR 1.04; 95 % CI 1.02-1.06). The accuracy of the model was 83 %, with 92 % of non-persistent and 67 % of persistent LBP patients correctly identified.
In this study of patients with acute/subacute LBP, 'resigned attitude towards the job' increased the likelihood of persistent LBP at 6 month. Addressing this factor with workplace interventions has the potential to modify the outcome. In patients experiencing 'social support at work', the development of persistent LBP was less likely and might therefore be considered as potential resource for prevention of persistent LBP.
为了减轻持续性腰痛(LBP)的社会经济负担,必须在早期识别出影响急性/亚急性 LBP 向持续性状态进展的因素。
对首次出现急性/亚急性或复发性 LBP 并就诊于医疗从业者的患者进行前瞻性起始队列研究。患者在基线时评估职业、心理、生物医学和人口统计学/生活方式因素,并在 6 个月内进行随访。对四个不同领域的变量组分别进行多变量逻辑回归分析,同时控制年龄、性别和体重指数。计算不同领域完整回归模型的总体预测值。最后,将不同领域的所有显著变量组合成一个最终预测模型。
最终的四因素预测模型预测了持续性 LBP 的 51%的方差,包括“对工作的无奈态度”(OR 1.73;95%CI 1.16-2.59)、“工作中的社会支持”(OR 0.54;95%CI 0.32-0.90)、“功能限制”(OR 1.05;95%CI 1.01-1.10)和“LBP 持续时间”(OR 1.04;95%CI 1.02-1.06)。该模型的准确性为 83%,92%的非持续性和 67%的持续性 LBP 患者得到正确识别。
在这项急性/亚急性 LBP 患者的研究中,“对工作的无奈态度”增加了 6 个月时持续性 LBP 的可能性。通过工作场所干预来解决这个因素有改变结果的潜力。在工作中“社会支持”的患者中,持续性 LBP 的发展可能性较小,因此可以考虑将其作为预防持续性 LBP 的潜在资源。