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肺癌机器人肺叶切除术的经验。

Experience with robotic lobectomy for lung cancer.

作者信息

Veronesi Giulia, Agoglia Bernardo G, Melfi Franca, Maisonneuve Patrick, Bertolotti Raffaella, Bianchi Paolo P, Rocco Bernardo, Borri Alessandro, Gasparri Roberto, Spaggiari Lorenzo

机构信息

Thoracic Surgery Division, European Institute of Oncology, Milan, Italy.

出版信息

Innovations (Phila). 2011 Nov;6(6):355-60. doi: 10.1097/IMI.0b013e3182490093.

Abstract

OBJECTIVE

In this study, we analyze our experience so far with robotic pulmonary lobectomy, compare it with published data, and suggest a learning curve for the operation.

METHODS

Ninety-one patients with suspected or proven clinical stage I-III lung cancer underwent robotic lobectomy. Selection criteria included lesion <5 cm and normal respiratory function. One surgeon performed the operations using the da Vinci system with three ports and a 3-cm utility thoracotomy.

RESULTS

Median duration of operation was 239 (range 85-411) minutes, 260 minutes in the first 18 patients and 221 minutes in the remaining 73 cases (P=0.01). Median hospitalization declined from 6 days in the first 18 cases to 5 days in the remaining cases (P=0.002). Conversion rate and number of complications reduced nonsignificantly from the initial to later series. Major complications occurred in 11% of the first 18 cases and 4% of the later cases. The number of lymph nodes removed did not change over the two series. There was no 30-day postoperative mortality. After a median follow-up of 24 months, 80 of 91 patients were alive with no sign of disease.

CONCLUSIONS

Our data suggest that about 20 operations are required to achieve surgical competence. Robotic lobectomy appears safe, oncologically radical, and associated with shorter postoperative hospitalization than open surgery.

摘要

目的

在本研究中,我们分析了目前在机器人辅助肺叶切除术中的经验,将其与已发表的数据进行比较,并提出该手术的学习曲线。

方法

91例疑似或确诊为临床I - III期肺癌的患者接受了机器人辅助肺叶切除术。选择标准包括病灶<5 cm且呼吸功能正常。由一名外科医生使用带有三个端口和一个3 cm辅助开胸切口的达芬奇系统进行手术。

结果

手术中位时长为239(范围85 - 411)分钟,前18例患者为260分钟,其余73例为221分钟(P = 0.01)。中位住院时间从最初18例的6天降至其余病例的5天(P = 0.002)。从最初阶段到后期阶段,中转率和并发症数量无显著降低。前18例中有11%发生主要并发症,后期病例中有4%发生。两个阶段切除的淋巴结数量没有变化。术后30天内无死亡病例。中位随访24个月后,91例患者中有80例存活且无疾病迹象。

结论

我们的数据表明,大约需要进行20例手术才能达到手术熟练程度。机器人辅助肺叶切除术似乎是安全的,具有肿瘤学根治性,并且与开放手术相比术后住院时间更短。

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