Khan A U, Todd S
Southern Illinois University School of Medicine, Springfield.
Psychiatry Res. 1990 Sep;33(3):313-20. doi: 10.1016/0165-1781(90)90048-a.
Ten adolescents with major depression and 10 age-matched controls were studied with polysomnography for 3 consecutive nights. The sleep records were analyzed for variables pertaining to sleep continuity (total sleep time, sleep efficiency, sleep onset latency, number of awakenings, and number of stage shifts), sleep architecture (Stages 1, 2, 3, and 4), and rapid eye movement (REM) sleep (total) REM sleep time, number of REM periods, REM latency, and REM density). The experimental and control groups were compared on 14 variables with the t test for independent groups. The results indicated that none of the sleep variables differed significantly between the two groups. These results confirm earlier findings indicating that the abnormalities in REM latency and REM density that characterize adults with major depression are absent in adolescents suffering from major depression. Developmental and diagnostic variables are discussed as possible explanations for the sleep differences between adolescents and adults with depressive disorders.
对10名患有重度抑郁症的青少年和10名年龄匹配的对照组进行了连续3晚的多导睡眠图研究。对睡眠记录进行分析，以获取与睡眠连续性（总睡眠时间、睡眠效率、入睡潜伏期、觉醒次数和睡眠阶段转换次数）、睡眠结构（第1、2、3和4阶段）以及快速眼动（REM）睡眠（总REM睡眠时间、REM周期数、REM潜伏期和REM密度）相关的变量。使用独立样本t检验对实验组和对照组的14个变量进行比较。结果表明，两组之间的睡眠变量均无显著差异。这些结果证实了早期的研究发现，即患有重度抑郁症的青少年不存在成年重度抑郁症患者所特有的REM潜伏期和REM密度异常。讨论了发育和诊断变量，作为青少年和成年抑郁症患者睡眠差异的可能解释。
