Riemann D, Kammerer J, Löw H, Schmidt M H
Psychiatric Clinic, University of Freiburg, Germany.
J Child Psychol Psychiatry. 1995 Feb;36(2):313-26. doi: 10.1111/j.1469-7610.1995.tb01827.x.
The present study aimed at investigating the question whether abnormalities of sleep, especially disinhibition of rapid eye movement (REM) sleep, are already present in adolescents with primary major depressive disorder (MDD). Ten healthy controls assessed at home, 10 inpatients with MDD and 10 inpatients with schizophrenia (age range: 13-19 years) were investigated polysomnographically. REM latency was significantly shortened in MDD compared with the two other groups. Adolescents with MDD did not display disturbances of sleep continuity as typically observed in adults with major depression. The most pronounced impairment of sleep continuity was noted in schizophrenic patients. The results stress that shortened REM latency may already occur in adolescent depression.
本研究旨在探讨原发性重度抑郁症（MDD）青少年是否已存在睡眠异常，尤其是快速眼动（REM）睡眠的去抑制现象。对10名在家接受评估的健康对照者、10名MDD住院患者和10名精神分裂症住院患者（年龄范围：13 - 19岁）进行了多导睡眠图检查。与其他两组相比，MDD患者的REM潜伏期显著缩短。患有MDD的青少年并未表现出像成年重度抑郁症患者中通常观察到的睡眠连续性障碍。睡眠连续性受损最明显的是精神分裂症患者。结果强调，REM潜伏期缩短可能在青少年抑郁症中已经出现。
