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骨质疏松性椎体压缩骨折经皮椎体成形术的长期随访:至少5年随访

Long-term Follow-up of Percutaneous Vertebroplasty in Osteoporotic Compression Fracture: Minimum of 5 Years Follow-up.

作者信息

Kim Jin Hwan, Yoo Si Hoon, Kim Jung Hoon

机构信息

Department of Orthopedic Surgery, Inje University Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.

出版信息

Asian Spine J. 2012 Mar;6(1):6-14. doi: 10.4184/asj.2012.6.1.6. Epub 2012 Mar 9.

Abstract

STUDY DESIGN

This was designed as a retrospective study.

PURPOSE

We assessed the radiographic and clinical outcome of patients who underwent percutaneous vertebroplasty (PVP) in osteoporotic compression fractures with a minimum of 5 years follow-up.

OVERVIEW OF LITERATURE

Percutaneous vertebroplasty is effective surgical method for treating osteoporotic compression fracture.

METHODS

Between January 2000 and August 2005, 159 patients were treated with PVP for osteoporotic compression fracture at our department; 43 patients died during follow-up, and 69 patients (121 vertebras) were available for follow-up for over 5 years. We analyzed the clinical and radiologic outcome including cement feature.

RESULTS

The mean follow-up period was 5.7 years. Clinical outcome by mean visual analogue scale (VAS) score revealed a decreased 4.9 points perioperatively. A decreased score was maintained over 5 years in 46% of patients. A new adjacent vertebral fracture was documented by 33 vertebral bodies in 22 patients. During the follow-up period, 43 patients (38%) in 112 patients died. Anterior body heig ht in the last follow-up was improved about 0.3 mm compared with the preprocedural value, but was not statistically significant. Also, the focal kyphotic angle was reduced from 12.3° at the preprocedural state to 11.7° at the postprocedural state, but was not statistically significant (p > 0.05).

CONCLUSIONS

PVP for osteoporotic compression fracture is an efficient procedure for pain relief by long term follow-up. The cement injected vertebrae showed stable radiologic progression without significant changes in vertebral height or kyphotic angle.

摘要

研究设计

本研究为回顾性研究。

目的

我们评估了接受经皮椎体成形术(PVP)治疗骨质疏松性压缩骨折且随访至少5年的患者的影像学和临床结果。

文献综述

经皮椎体成形术是治疗骨质疏松性压缩骨折的有效手术方法。

方法

2000年1月至2005年8月期间,我科159例骨质疏松性压缩骨折患者接受了PVP治疗;43例患者在随访期间死亡,69例患者(121个椎体)随访超过5年。我们分析了包括骨水泥特征在内的临床和放射学结果。

结果

平均随访期为5.7年。平均视觉模拟量表(VAS)评分显示围手术期下降了4.9分。46%的患者在5年以上保持了分数下降。22例患者的33个椎体记录有新的相邻椎体骨折。随访期间,112例患者中有43例(38%)死亡。最后一次随访时的椎体前缘高度与术前相比提高了约0.3mm,但无统计学意义。此外,局部后凸角从术前的12.3°降至术后的11.7°,但无统计学意义(p>0.05)。

结论

PVP治疗骨质疏松性压缩骨折是一种通过长期随访有效缓解疼痛的方法。注入骨水泥的椎体显示出稳定的放射学进展,椎体高度或后凸角无明显变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9938/3302917/39e8e3ec2586/asj-6-6-g001.jpg

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