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抗肿瘤治疗引起的口腔黏膜炎的预防与管理

Prevention and management of antineoplastic therapy induced oral mucositis.

作者信息

Bey Afshan, Ahmed Syed S, Hussain Bilal, Devi Seema, Hashmi Sarwat H

机构信息

Department of Periodontics and Community Dentistry, Dr. Z.A. Dental College, Aligarh Muslim University, Aligarh, India.

出版信息

Natl J Maxillofac Surg. 2010 Jul;1(2):127-34. doi: 10.4103/0975-5950.79214.

DOI:10.4103/0975-5950.79214
PMID:22442583
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3304209/
Abstract

With the scientific advancements in the management of malignant diseases, the treatment is expensive and bears high morbidity in term of oral mucositis. It is a debilitating condition and has been researched extensively for its pathogenesis and treatment. Various treatment options include barrier forming, mucosal protectants, mouth rinses, growth factors, lasers and midline-sparing procedures. Some agents are used locally while others are administered systemically. Despite the availability of a wide range of treatment options for mucositis, a cost-effective treatment is yet to be evolved.

摘要

随着恶性疾病治疗方面的科学进步,治疗费用高昂,且就口腔黏膜炎而言发病率很高。它是一种使人虚弱的病症,其发病机制和治疗方法已得到广泛研究。各种治疗选择包括形成屏障、使用黏膜保护剂、漱口水、生长因子、激光和中线保留手术。一些药物是局部使用,而其他药物则是全身给药。尽管有多种治疗口腔黏膜炎的选择,但尚未找到一种具有成本效益的治疗方法。

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J Appl Oral Sci. 2003 Dec;11(4):337-41. doi: 10.1590/s1678-77572003000400012.
2
Serum amyloid P ameliorates radiation-induced oral mucositis and fibrosis.血清淀粉样蛋白P可改善辐射诱导的口腔黏膜炎和纤维化。
Fibrogenesis Tissue Repair. 2010 Jul 5;3:11. doi: 10.1186/1755-1536-3-11.
3
Double-blind, placebo-controlled, randomized study of chlorhexidine prophylaxis for 5-fluorouracil-based chemotherapy-induced oral mucositis with nonblinded randomized comparison to oral cooling (cryotherapy) in gastrointestinal malignancies.氯己定预防基于5-氟尿嘧啶的化疗引起的口腔黏膜炎的双盲、安慰剂对照、随机研究,并与胃肠道恶性肿瘤中的口腔冷却(冷冻疗法)进行非盲随机比较。
Cancer. 2008 Apr 1;112(7):1600-6. doi: 10.1002/cncr.23328.
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Effect of epidermal growth factor against radiotherapy-induced oral mucositis in rats.表皮生长因子对大鼠放射性口腔黏膜炎的影响。
Int J Radiat Oncol Biol Phys. 2007 Mar 15;67(4):1172-8. doi: 10.1016/j.ijrobp.2006.10.038.
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10
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J Clin Nurs. 2005 Jul;14(6):754-65. doi: 10.1111/j.1365-2702.2005.01128.x.