Division of Endocrinology and Metabolism, Department of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon, Seoul, Korea.
Diabet Med. 2012 Nov;29(11):1395-8. doi: 10.1111/j.1464-5491.2012.03661.x.
The optimal anthropometric measure of obesity or body fat distribution that best predicts the risk of Type 2 diabetes in Asians is unclear. Moreover, it has not been determined whether BMI modifies the effect of body fat distribution on diabetes risk in Asians.
We analysed the anthropometric and laboratory data of 7658 non-diabetic Korean adults (5061 men and 2597 women, aged 20-79 years) who underwent routine medical check-ups at 5-year intervals. BMI, waist circumference, waist-to-height ratio, and bioelectrical impedance (to calculate fat mass and per cent body fat) were measured at baseline.
Of the 7658 participants, 278 subjects (3.6%) developed diabetes over 5 years. Each of the anthropometric measures of general obesity (BMI, fat mass, per cent body fat) and central body fat distribution (waist circumference and waist-to-height ratio) was a good predictor of Type 2 diabetes. However, when the areas under the receiver-operating characteristic curves were compared, BMI (0.697; 95% CI, 0.669-0.725), waist circumference (0.709, 0.682-0.736) and waist-to-height ratio (0.718, 0.692-0.743) were better predictors of diabetes risk than fat mass (0.672, 0.643-0.700) or per cent body fat (0.657, 0.628-0.686). In the low- (< 23 kg/m(2)) and mid- (23-27 kg/m(2)) BMI groups, the addition of waist-to-height ratio or waist circumference to BMI could improve the prediction of diabetes risk.
BMI, waist circumference and waist-to-height ratio were good predictors of Type 2 diabetes risk in Koreans. In non-obese or less obese subjects, measures of central body fat distribution can help improve the prediction of Type 2 diabetes risk when added to measures of general obesity.
对于亚洲人而言，哪种肥胖或体脂分布的最佳人体测量指标能够最佳预测 2 型糖尿病风险尚不清楚。此外，还不能确定 BMI 是否会改变体脂分布对亚洲人糖尿病风险的影响。
我们分析了 7658 名非糖尿病韩国成年人（5061 名男性和 2597 名女性，年龄 20-79 岁）的人体测量和实验室数据，这些人每 5 年接受一次常规体检。在基线时测量了 BMI、腰围、腰高比和生物电阻抗（以计算脂肪量和体脂百分比）。
在 7658 名参与者中，278 名（3.6%）在 5 年内患上了糖尿病。一般肥胖（BMI、脂肪量、体脂百分比）和中心性体脂分布（腰围和腰高比）的各项人体测量指标都是 2 型糖尿病的良好预测指标。然而，当比较受试者工作特征曲线下的面积时，BMI（0.697；95%CI，0.669-0.725）、腰围（0.709，0.682-0.736）和腰高比（0.718，0.692-0.743）比脂肪量（0.672，0.643-0.700）或体脂百分比（0.657，0.628-0.686）更好地预测了糖尿病风险。在低（<23kg/m2）和中（23-27kg/m2）BMI 组中，将腰高比或腰围添加到 BMI 中可以提高糖尿病风险的预测能力。
BMI、腰围和腰高比是韩国人 2 型糖尿病风险的良好预测指标。在非肥胖或肥胖程度较低的人群中，中心性体脂分布的测量指标可以帮助改善对 2 型糖尿病风险的预测，当与一般肥胖的测量指标一起使用时。
