Division of Cardiology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Kanagawa, Japan.
J Cardiol. 2012 Jul;60(1):55-60. doi: 10.1016/j.jjcc.2012.01.014. Epub 2012 Mar 21.
Speckle tracking echocardiography (STE)-derived mitral annular displacement (MAD) utilizes the speckle tracking technique to measure strain vectors, which provides accurate estimates of left ventricular ejection fraction (LVEF). Here, we investigated a link between STE-derived MAD and LVEF in patients with different heart diseases and evaluated its clinical usefulness.
This study included 266 outpatients and 84 controls. Of the study patients, 52 patients had ischemic heart disease (IHD), 37 patients had dilated cardiomyopathy (DCM), 34 patients had hypertrophic cardiomyopathy (HCM), 74 patients had valvular heart disease (VHD), and 69 patients had hypertensive heart disease (HHD). STE continuously tracked annular motion throughout the cardiac cycle in the apical 4- and 2-chamber views.
In all participants, the curvilinear relationship was found between STE-derived MAD and LVEF (R(2)=0.642). The strong correlation between STE-derived MAD and LVEF was also found in the patients with IHD (R(2)=0.733, p=0.001) and in those with DCM (R(2)=0.614, p=0.008). However, such a correlation was not found in the patients with HCM, VHD, or HHD.
The specificity in the correlation between STE-derived MAD and LVEF was found in patients with each heart disease, which should be taken into account when assessing these parameters.
斑点追踪超声心动图（STE）衍生的二尖瓣环位移（MAD）利用斑点追踪技术测量应变向量，可准确估计左心室射血分数（LVEF）。在这里，我们研究了不同心脏病患者中 STE 衍生 MAD 与 LVEF 之间的关系，并评估了其临床应用价值。
本研究纳入 266 名门诊患者和 84 名对照者。研究患者中，52 例为缺血性心脏病（IHD），37 例为扩张型心肌病（DCM），34 例为肥厚型心肌病（HCM），74 例为瓣膜性心脏病（VHD），69 例为高血压性心脏病（HHD）。STE 在心尖 4 腔和 2 腔切面连续追踪整个心动周期的环形运动。
在所有参与者中，STE 衍生 MAD 与 LVEF 之间呈曲线关系（R(2)=0.642）。在 IHD 患者（R(2)=0.733，p=0.001）和 DCM 患者（R(2)=0.614，p=0.008）中，STE 衍生 MAD 与 LVEF 之间也存在很强的相关性。然而，在 HCM、VHD 或 HHD 患者中未发现这种相关性。
在每种心脏病患者中，STE 衍生 MAD 与 LVEF 之间的相关性存在特异性，在评估这些参数时应考虑到这一点。
