Charité - Universitätsmedizin Berlin, Berlin School of Public Health, Seestraße 73, Berlin 13347, Germany.
BMC Womens Health. 2012 Mar 26;12:6. doi: 10.1186/1472-6874-12-6.
In 2009 the Uterine Bleeding and Pain Women's Research Study (UBP-WRS) was conducted interviewing 21,479 women across 8 countries in order to gain patient-based prevalence data on uterine pain and bleeding indications and investigate uterine symptoms and women's treatment experiences. This article shows relevant results of the study for the indication uterine fibroids providing data on self-reported prevalence, symptomatology and management of uterine fibroids.
2,500 women (USA: 4,500 women) in each country (Brazil, Canada, France, Germany, Italy, South Korea, the UK, the USA) completed an online survey. Women included were in their reproductive age (age group 15-49 years; USA: 18-49 years) and had ever experienced menstrual bleedings. Quotas were applied for age, region, level of education and household income of respondents. Variables have been analyzed descriptively and exploratory statistical tests have been performed.
The self-reported prevalence of uterine fibroids ranged from 4.5% (UK) to 9.8% (Italy), reaching 9.4% (UK) to 17.8% (Italy) in the age group of 40-49 years. Women with a diagnosis of uterine fibroids reported significantly more often about bleeding symptoms than women without a diagnosis: heavy bleedings (59.8% vs. 37.4%), prolonged bleedings (37.3% vs. 15.6%), bleeding between periods (33.3% vs. 13.5%), frequent periods (28.4% vs. 15.2%), irregular and predictable periods (36.3% vs. 23.9%). Furthermore women with diagnosed uterine fibroids reported significantly more often about the following pain symptoms: pressure on the bladder (32.6% vs. 15.0%), chronic pelvic pain (14.5% vs. 2.9%), painful sexual intercourse (23.5% vs. 9.1%) and pain occurring mid-cycle, after and during menstrual bleeding (31.3%, 16.7%, 59.7%, vs. 17.1%, 6.4%, 52.0%). 53.7% of women reported that their symptoms had a negative impact on their life in the last 12 month, influencing their sexual life (42.9%), performance at work (27.7%) and relationship & family (27.2%).
Uterine fibroid is a common concern in women at fertile age causing multiple bleeding and pain symptoms which can have a negative impact on different aspects in women's life.
2009 年，开展了“子宫出血和疼痛女性研究（UBP-WRS）”，该研究对 8 个国家的 21479 名妇女进行了访谈，旨在获得基于患者的关于子宫疼痛和出血指征的流行率数据，并调查子宫症状和妇女的治疗经验。本文展示了该研究与子宫纤维瘤指征相关的结果，提供了关于自我报告的流行率、症状和子宫纤维瘤管理的数据。
每个国家（巴西、加拿大、法国、德国、意大利、韩国、英国、美国）各有 2500 名女性（美国：4500 名女性）完成了在线调查。纳入的妇女处于生育年龄（年龄组 15-49 岁；美国：18-49 岁），并经历过月经出血。对受访者的年龄、地区、教育水平和家庭收入进行了配额。对变量进行了描述性分析，并进行了探索性统计检验。
子宫纤维瘤的自我报告流行率从英国的 4.5%（英国）到意大利的 9.8%（意大利）不等，40-49 岁年龄组的流行率达到英国的 9.4%（英国）到意大利的 17.8%（意大利）。被诊断患有子宫纤维瘤的妇女报告出血症状的频率明显高于未被诊断的妇女：大量出血（59.8%比 37.4%）、出血时间延长（37.3%比 15.6%）、月经间期出血（33.3%比 13.5%）、月经频繁（28.4%比 15.2%）、不规律且可预测的经期（36.3%比 23.9%）。此外，诊断为子宫纤维瘤的妇女报告以下疼痛症状的频率明显更高：膀胱受压（32.6%比 15.0%）、慢性盆腔疼痛（14.5%比 2.9%）、性交疼痛（23.5%比 9.1%）以及在月经中期、之后和期间出现疼痛（31.3%、16.7%、59.7%比 17.1%、6.4%、52.0%）。53.7%的妇女报告说，她们的症状在过去 12 个月对她们的生活产生了负面影响，影响了她们的性生活（42.9%）、工作表现（27.7%）和人际关系和家庭（27.2%）。
子宫纤维瘤是生育期妇女常见的关注点，会导致多种出血和疼痛症状，这些症状会对妇女生活的各个方面产生负面影响。
