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[直立性震颤:一种神秘病症]

[Orthostatic tremor: an enigmatic condition].

作者信息

Labiano-Fontcuberta A, Benito-Leon J, Dominguez-Gonzalez C

机构信息

Hospital Universitario 12 de Octubre, Madrid, Espana.

出版信息

Rev Neurol. 2012 Apr 1;54(7):425-34.

Abstract

INTRODUCTION

Orthostatic tremor is a rare kind of tremor which is clinically characterised by a feeling of instability or being about to fall that is experienced on standing up, which disappears or improves on walking and is absent when sitting or lying down.

AIM

To shed light on the main features of this tremor syndrome.

DEVELOPMENT

First, its clinical spectrum is defined, with emphasis on the key characteristics that enable us to make an initial approximation to its syndromes. Then the main neurophysiological features that make up the electromyographic profile of orthostatic tremor are described. Finally, the pathophysiological hypotheses regarding the genesis of this kind of tremor are addressed and the therapeutic options currently available are described.

CONCLUSIONS

The convergence of all the data reviewed provides a complete, critical analysis of this enigmatic motor disorder, thus allowing a rigorous approach to its main characteristics, which makes both its clinical recognition and its therapeutic management easier.

摘要

引言

直立性震颤是一种罕见的震颤,其临床特征是站立时会感到不稳定或即将跌倒,行走时这种感觉消失或改善,坐着或躺着时则不存在。

目的

阐明这种震颤综合征的主要特征。

进展

首先,界定其临床范围,重点关注能够使我们初步了解其综合征的关键特征。然后描述构成直立性震颤肌电图特征的主要神经生理学特征。最后,探讨关于这种震颤发生机制的病理生理学假说,并描述目前可用的治疗选择。

结论

所综述的所有数据汇总在一起,对这种神秘的运动障碍进行了全面、批判性的分析,从而能够严谨地探讨其主要特征,这使得其临床识别和治疗管理都更加容易。

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