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解读时间、信心水平与乳腺 X 光筛查准确性之间的关系。

Association between time spent interpreting, level of confidence, and accuracy of screening mammography.

机构信息

Department of Family Medicine, Oregon Health & Science University, Portland, 97239, USA.

出版信息

AJR Am J Roentgenol. 2012 Apr;198(4):970-8. doi: 10.2214/AJR.11.6988.

Abstract

OBJECTIVE

The objective of this study was to examine the effect of time spent viewing images and level of confidence on a screening mammography test set on interpretive performance.

MATERIALS AND METHODS

Radiologists from six mammography registries participated in this study and were randomized to interpret one of four test sets and complete 12 survey questions. Each test set had 109 cases of digitized four-view screening screen-film mammograms with prior comparison screening views. Viewing time for each case was defined as the cumulative time spent viewing all mammographic images before recording which visible feature, if any, was the "most significant finding." Log-linear regression fit via the generalized estimating equation was used to test the effect of viewing time and level of confidence in the interpretation on test set sensitivity and false-positive rate.

RESULTS

One hundred nineteen radiologists completed a test set and contributed data on 11,484 interpretations. The radiologists spent more time viewing cases that had significant findings or cases for which they had less confidence in their interpretation. Each additional minute of viewing time increased the probability of a true-positive interpretation among cancer cases by 1.12 (95% CI, 1.06-1.19; p < 0.001) regardless of confidence in the assessment. Among the radiologists who were very confident in their assessment, each additional minute of viewing time increased the adjusted risk of a false-positive interpretation among noncancer cases by 1.42 (95% CI, 1.21-1.68), and this viewing-time effect diminished with decreasing confidence.

CONCLUSION

Longer interpretation times and higher levels of confidence in an interpretation are both associated with higher sensitivity and false-positive rates in mammography screening.

摘要

目的

本研究旨在探讨在筛查性乳房 X 光摄影检查中,观看图像的时间和置信度水平对检测结果的影响。

材料与方法

来自六个乳房 X 光摄影登记处的放射科医生参与了这项研究,并随机分配到四个测试集中的一个,并完成了 12 个调查问题。每个测试集都有 109 例数字化四视图筛查屏片乳房 X 光照片,附有先前的比较筛查视图。每个病例的观看时间定义为观看所有乳腺 X 光图像的累计时间,然后记录哪些可见特征(如果有)是“最显著的发现”。通过广义估计方程进行对数线性回归拟合,以测试观看时间和对解释的置信度对测试集敏感性和假阳性率的影响。

结果

119 名放射科医生完成了一个测试集,并对 11484 次解释数据做出了贡献。放射科医生花费更多的时间观看有显著发现或对其解释缺乏信心的病例。观看时间每增加一分钟,癌症病例中真阳性解释的可能性就会增加 1.12 倍(95%CI,1.06-1.19;p<0.001),无论对评估的信心如何。在对自己的评估非常有信心的放射科医生中,观看时间每增加一分钟,非癌症病例中假阳性解释的调整风险就会增加 1.42 倍(95%CI,1.21-1.68),并且这种观看时间的影响随着信心的降低而减弱。

结论

更长的解释时间和对解释的更高置信度都与乳房 X 光摄影筛查中的更高敏感性和更高假阳性率相关。

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