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角膜内皮细胞丢失与白内障超声乳化切口位置的相关性

Correlation between Corneal Endothelial Cell Loss and Location of Phacoemulsification Incision.

作者信息

Gharaee Hamid, Kargozar Abbas, Daneshvar-Kakhki Ramin, Sharepour Maria, Hassanzadeh Samira

机构信息

Department of Ophthalmology, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

J Ophthalmic Vis Res. 2011 Jan;6(1):13-7.

Abstract

PURPOSE

To assess the relationship between corneal endothelial cell loss after phacoemulsification and the location of the clear corneal incision.

METHODS

A total of 92 patients (92 eyes) with senile cataracts who met the study criteria were included in this cross sectional study and underwent phacoemulsification. The incision site was determined based on the steep corneal meridian according to preoperative keratometry. Endothelial cell density was measured using specular microscopy in the center and 3 mm from the center of the cornea in the meridian of the incisions (temporal, superior, and superotemporal). Phacoemulsification was performed by a single surgeon using the phaco chop technique through a 3.2 mm clear cornea incision. Endothelial cell loss (ECL) was evaluated 1 week, and 1 and 3 months postoperatively.

RESULTS

At all time points during follow-up, ECL was comparable among the 3 incision sites, both in the central cornea and in the meridian of the incision (P > 0.05 for all comparisons). However, 3 months postoperatively, mean central ECL with superior incisions and mean sectoral ECL with temporal incisions were slightly higher. Superotemporal incisions entailed slightly less ECL than the other 2 groups. Overall, one month after surgery, mean central ECL was 10.8% and mean ECL in the sector of the incisions was 14.0%. Axial length and effective phaco time (EFT) were independent predictors of postoperative central ECL (P values 0.005 and < 0.0001, respectively).

CONCLUSION

A superotemporal phacoemulsification incision may entail less ECL as compared to other incisions (although not significantly different). The amount of central ECL may be less marked in patients with longer axial lengths and with procedures utilizing less EFT.

摘要

目的

评估白内障超声乳化术后角膜内皮细胞丢失与透明角膜切口位置之间的关系。

方法

本横断面研究纳入了92例符合研究标准的老年性白内障患者(92只眼),并对其进行了超声乳化手术。根据术前角膜曲率计测量的陡峭角膜子午线确定切口位置。使用镜面显微镜测量角膜中央以及切口子午线方向距角膜中央3mm处的内皮细胞密度(颞侧、上方和颞上方)。由一名外科医生采用超声劈核技术通过3.2mm透明角膜切口进行超声乳化手术。在术后1周、1个月和3个月评估内皮细胞丢失(ECL)情况。

结果

在随访的所有时间点,3个切口位置在角膜中央和切口子午线方向的ECL均相当(所有比较的P>0.05)。然而,术后3个月,上方切口的平均中央ECL和颞侧切口的平均扇形ECL略高。颞上方切口的ECL略低于其他两组。总体而言,术后1个月,平均中央ECL为10.8%,切口扇形区域的平均ECL为14.0%。眼轴长度和有效超声乳化时间(EFT)是术后中央ECL的独立预测因素(P值分别为0.005和<0.0001)。

结论

与其他切口相比,颞上方超声乳化切口可能导致较少的ECL(尽管差异不显著)。眼轴较长且EFT较短的患者中央ECL量可能较少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c5fb/3306078/70cd58a8990a/jovr-6-1-013f1.jpg

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