Chylack L T, Wolfe J K, Singer D M, Leske M C, Bullimore M A, Bailey I L, Friend J, McCarthy D, Wu S Y
Center for Clinical Cataract Research, Brigham and Women's Hospital, Boston, Mass. 02115.
Arch Ophthalmol. 1993 Jun;111(6):831-6. doi: 10.1001/archopht.1993.01090060119035.
To develop the Lens Opacities Classification System III (LOCS III) to overcome the limitations inherent in lens classification using LOCS II. These limitations include unequal intervals between standards, only one standard for color grading, use of integer grading, and wide 95% tolerance limits.
The LOCS III contains an expanded set of standards that were selected from the Longitudinal Study of Cataract slide library at the Center for Clinical Cataract Research, Boston, Mass. It consists of six slit-lamp images for grading nuclear color (NC) and nuclear opalescence (NO), five retroillumination images for grading cortical cataract (C), and five retroillumination images for grading posterior subcapsular (P) cataract. Cataract severity is graded on a decimal scale, and the standards have regularly spaced intervals on a decimal scale. The 95% tolerance limits are reduced from 2.0 for each class with LOCS II to 0.7 for nuclear opalescence, 0.7 for nuclear color, 0.5 for cortical cataract, and 1.0 for posterior subcapsular cataract with the LOCS III, with excellent interobserver agreement.
The LOCS III is an improved LOCS system for grading slit-lamp and retroillumination images of age-related cataract.
开发晶状体混浊分类系统III（LOCS III），以克服使用LOCS II进行晶状体分类时固有的局限性。这些局限性包括标准之间的间隔不均、颜色分级仅有一个标准、使用整数分级以及95%的宽公差限度。
LOCS III包含一组扩展的标准，这些标准选自马萨诸塞州波士顿临床白内障研究中心的白内障纵向研究幻灯片库。它由六张裂隙灯图像用于分级核颜色（NC）和核混浊度（NO）、五张后照图像用于分级皮质性白内障（C）以及五张后照图像用于分级后囊下（P）白内障。白内障严重程度采用十进制分级，且标准在十进制尺度上具有等间距。95%的公差限度从LOCS II时每个类别2.0降低到LOCS III时核混浊度为0.7、核颜色为0.7、皮质性白内障为0.5以及后囊下白内障为1.0，观察者间一致性良好。
LOCS III是用于分级年龄相关性白内障裂隙灯和后照图像的改进型LOCS系统。
