食物和运动对泡腾阿司匹林吸收的影响。
Effects of food and exercise on the absorption of effervescent aspirin.
机构信息
The Princess Margaret Migraine Clinic, 22 Charterhouse Square, London; Department of Clinical Pharmacology, St. Bartholomew's Hospital, London.
出版信息
Br J Clin Pharmacol. 1974 Apr;1(2):137-41. doi: 10.1111/j.1365-2125.1974.tb00222.x.
Abstract
1 The absorption of effervescent aspirin was studied in normal volunteers of both sexes under varied conditions of activity in both fasting and non-fasting states. 2 Moderate activity resulted in no significant changes in absorption compared with that at rest. 3 In non-fasting subjects the absorption was reduced but this reduction was attenuated with time until after 60 min the plasma levels were similar. 4 There was no interaction between the resting/non-resting and fasting/non-fasting absorption.
摘要
在禁食和不禁食状态下，在不同活动条件下，研究了两性正常志愿者对泡腾阿司匹林的吸收情况。
与休息时相比，适度活动对吸收没有显著影响。
在非禁食受试者中，吸收减少，但随着时间的推移，这种减少得到缓解，直到 60 分钟后，血浆水平相似。
休息/不休息和禁食/不禁食吸收之间没有相互作用。
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