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1
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本文引用的文献

1
FACTORS INFLUENCING THE PLASMA SALICYLATE CONCENTRATION AND URINARY SALICYLATE EXCRETION AFTER ORAL DOSAGE WITH ASPIRIN.口服阿司匹林后影响血浆水杨酸浓度及尿中水杨酸排泄的因素
Biochem Pharmacol. 1964 May;13:767-76. doi: 10.1016/0006-2952(64)90013-9.
2
GASTROINTESTINAL FACTORS IN ASPIRIN ABSORPTION. A QUANTITATIVE STUDY.阿司匹林吸收中的胃肠道因素。一项定量研究。
J Pharm Sci. 1964 Feb;53:129-34. doi: 10.1002/jps.2600530203.
3
EFFECT OF CERTAIN TABLET FORMULATION FACTORS ON DISSOLUTION RATE OF THE ACTIVE INGREDIENT. III. TABLET LUBRICANTS.
J Pharm Sci. 1963 Dec;52:1139-44. doi: 10.1002/jps.2600521209.
4
GASTRIC EMPTYING IN RELATION TO DRUG ABSORPTION.与药物吸收相关的胃排空
Am J Dig Dis. 1963 Nov;8:885-94. doi: 10.1007/BF02232082.
5
The effect of elevated body temperature and of stress on the motility of stomach and colon in man.体温升高及应激对人体胃和结肠运动的影响。
Clin Sci. 1968 Feb;34(1):149-59.
6
Propulsion (mass movements) in the human colon and its relationship to meals and somatic activity.人类结肠的推进运动（集团蠕动）及其与进餐和躯体活动的关系。
Gut. 1970 Feb;11(2):91-9. doi: 10.1136/gut.11.2.91.
7
Effects of dietary components on GI absorption of acetaminophen tablets in man.饮食成分对人体对乙酰氨基酚片胃肠道吸收的影响。
J Pharm Sci. 1971 Nov;60(11):1646-50. doi: 10.1002/jps.2600601111.
8
The formulation of aspirin.阿司匹林的配方。
Adv Pharm Sci. 1971;3:107-71.
9
Decrease of tetracycline absorption in man by sodium bicarbonate.
Clin Pharmacol Ther. 1971 Sep-Oct;12(5):779-84. doi: 10.1002/cpt1971125779.
10
Blood flow and gastrointestinal function.血流与胃肠功能。
Gastroenterology. 1971 Feb;60(2):325-35.

食物和运动对泡腾阿司匹林吸收的影响。

Effects of food and exercise on the absorption of effervescent aspirin.

机构信息

The Princess Margaret Migraine Clinic, 22 Charterhouse Square, London; Department of Clinical Pharmacology, St. Bartholomew's Hospital, London.

出版信息

Br J Clin Pharmacol. 1974 Apr;1(2):137-41. doi: 10.1111/j.1365-2125.1974.tb00222.x.

DOI:10.1111/j.1365-2125.1974.tb00222.x
PMID:22454900
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1402447/
Abstract

1 The absorption of effervescent aspirin was studied in normal volunteers of both sexes under varied conditions of activity in both fasting and non-fasting states. 2 Moderate activity resulted in no significant changes in absorption compared with that at rest. 3 In non-fasting subjects the absorption was reduced but this reduction was attenuated with time until after 60 min the plasma levels were similar. 4 There was no interaction between the resting/non-resting and fasting/non-fasting absorption.

摘要

  1. 在禁食和不禁食状态下，在不同活动条件下，研究了两性正常志愿者对泡腾阿司匹林的吸收情况。

  2. 与休息时相比，适度活动对吸收没有显著影响。

  3. 在非禁食受试者中，吸收减少，但随着时间的推移，这种减少得到缓解，直到 60 分钟后，血浆水平相似。

  4. 休息/不休息和禁食/不禁食吸收之间没有相互作用。