Department of Psychiatry and Behavioral Sciences, Tulane University, New Orleans, Louisiana, USA.
J Addict Med. 2012 Jun;6(2):177-8. doi: 10.1097/ADM.0b013e3182486e44.
Buprenorphine/naloxone is used for the treatment of opioid dependence. In the following case, a potential use for the medication combination is explored in the arena of transplant surgery. Psychiatry was consulted for a 29-year-old woman with iatrogenic opioid dependence after bilateral ventricular assist device placement for congenital cardiomyopathy. Her ejection fraction was less than 15% and she was considered a poor candidate for transplant due to drug-seeking behaviors. We transitioned her onto buprenorphine/naloxone to prevent abuse and control symptoms, qualifying her for cardiac transplant. After transplant, we coordinated care with cardiothoracic surgeons to restart buprenorphine/naloxone, and the patient has been stable for 8 months.
丁丙诺啡/纳洛酮用于治疗阿片类药物依赖。在以下病例中，探讨了药物联合在移植手术领域的潜在用途。一名 29 岁女性因先天性心肌病行双侧心室辅助装置植入术后出现医源性阿片类药物依赖，我们咨询了精神病学。她的射血分数低于 15%，由于觅药行为，她被认为是移植的不适合人选。我们将她转为丁丙诺啡/纳洛酮，以防止滥用和控制症状，使她有资格进行心脏移植。移植后，我们与心胸外科医生协调以重新开始使用丁丙诺啡/纳洛酮，患者情况稳定 8 个月。
