微阵列上的氧酯介导的天然化学连接：一种高效和选择性化学偶联方法。
Oxo-ester mediated native chemical ligation on microarrays: an efficient and chemoselective coupling methodology.
机构信息
School of Chemistry & Manchester Interdisciplinary Biocentre, The University of Manchester, 131 Princess Street, Manchester M17DN, UK.
出版信息
Chem Commun (Camb). 2012 May 11;48(37):4444-6. doi: 10.1039/c2cc30844d. Epub 2012 Mar 28.
PMID:22456682
Abstract
We report a highly efficient and selective method for the coupling of peptides and glycoconjugates bearing N-terminal cysteines to activated surfaces. This chemoselective method generates stable amide linkages without using any thiol additives.
摘要
我们报道了一种高效且选择性的方法，用于将带有 N-末端半胱氨酸的肽和糖缀合物偶联到活化表面上。这种化学选择性方法在不使用任何硫醇添加剂的情况下生成稳定的酰胺键。
Zotero 插件