Polyakova V O, Linkova N S, Kvetnoy I M, Khavinson V Kh
St. Petersburg Institute of Bioregulation and Gerontology, North Western Division of the Russian Academy of Medical Sciences, Russia.
Bull Exp Biol Med. 2011 Sep;151(5):627-30. doi: 10.1007/s10517-011-1400-2.
The data on the morphology and functions of the thymus and pineal gland in individuals of different age are analyzed and common mechanisms of involution of these organs during aging and the consequencies of this process are discussed. Based on the data on the molecular changes in the thymus and pineal gland during aging, the authors hypothesize the functional unity of these organs and their mutual complementarity in the maintenance of normal immune and endocrine status during aging.
分析了不同年龄段个体胸腺和松果体的形态学及功能数据,并探讨了这些器官在衰老过程中退化的共同机制及其后果。基于衰老过程中胸腺和松果体分子变化的数据,作者推测这些器官在维持衰老过程中正常免疫和内分泌状态方面的功能统一性及其相互补充性。