Valid Nutrition, Nairobi, Kenya Valid International, Lusaka, Zambia Valid International, Oxford, UK.
Matern Child Nutr. 2014 Jan;10(1):126-34. doi: 10.1111/j.1740-8709.2012.00400.x. Epub 2012 Mar 29.
Peanut milk-based ready-to-use therapeutic food (P-RUTF) primarily used to treat severe acute malnutrition at community setting is expensive. We developed an alternative milk-free soybean-maize-sorghum-based RUTF (SMS-RUTF) using locally grown ingredients that have the potential to support local economy and reduce the cost of RUTF. We describe the production process and results of acceptability of the new product. Acceptability and tolerance of SMS-RUTF was compared with P-RUTF among 45 children aged 4-11 years old based on a cross-over design. Each child consumed 250 g RUTF for 10 days followed by a five-day washout period and a subsequent 10-day period on the second RUTF. The SMS-RUTF was as acceptable as the P-RUTF among normal children aged 4-11 years of age with no associated adverse effects. SMS-RUTF was stable for at least 12 months without detectable microbiological or chemical deterioration. The major challenge encountered in SMS-RUTF development was the difficulty to accurately determine key nutrient composition due to its high oil content. Use of diversified locally available ingredients to produce RUTF is feasible. The SMS-RUTF meets expected standards and is acceptable to children aged 4-11 months old. Effectiveness and cost-effectiveness of SMS-RUTF is required.
以花生奶为基础的即食治疗食品(P-RUTF)主要用于社区环境中治疗严重急性营养不良,但价格昂贵。我们开发了一种替代的不含牛奶的基于大豆-玉米-高粱的 RUTF(SMS-RUTF),使用了当地种植的原料,具有支持当地经济和降低 RUTF 成本的潜力。我们描述了新产品的生产过程和可接受性结果。在基于交叉设计的 45 名 4-11 岁儿童中,比较了 SMS-RUTF 和 P-RUTF 的可接受性和耐受性。每个孩子连续 10 天食用 250g RUTF,然后进行 5 天的洗脱期,随后再食用第二种 RUTF 10 天。SMS-RUTF 在正常 4-11 岁儿童中与 P-RUTF 一样可接受,没有相关的不良反应。SMS-RUTF 至少稳定 12 个月,没有发现微生物或化学恶化。在 SMS-RUTF 开发过程中遇到的主要挑战是由于其高油含量,难以准确确定关键营养成分。使用多样化的当地可用原料生产 RUTF 是可行的。SMS-RUTF 符合预期标准,可被 4-11 个月大的儿童接受。需要评估 SMS-RUTF 的有效性和成本效益。