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功能能力是预测黑人和白人冠心病的更好指标,优于抑郁或睡眠时长异常。

Functional capacity is a better predictor of coronary heart disease than depression or abnormal sleep duration in Black and White Americans.

机构信息

Brooklyn Health Disparities Center, Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY 11203-2098, USA.

出版信息

Sleep Med. 2012 Jun;13(6):728-31. doi: 10.1016/j.sleep.2012.01.015. Epub 2012 Mar 31.

DOI:10.1016/j.sleep.2012.01.015
PMID:22465451
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3372763/
Abstract

OBJECTIVE

To assess whether functional capacity is a better predictor of coronary heart disease (CHD) than depression or abnormal sleep duration.

METHODS

Adult civilians in the USA (n=29,818, mean age 48 ± 18 years, range 18-85 years) were recruited by a cross-sectional household interview survey using multistage area probability sampling. Data on chronic conditions, estimated habitual sleep duration, functional capacity, depressed moods, and sociodemographic characteristics were obtained.

RESULTS

Thirty-five percent of participants reported reduced functional capacity. The CHD rates among White and Black Americans were 5.2% and 4%, respectively. Individuals with CHD were more likely to report extreme sleep durations (short sleep [≤ 5h] or long sleep [≥ 9 h]; odds ratio [OR] 1.65, 95% confidence interval [CI] 1.38-1.97; P<0.0001), less likely to be functionally active (anchored by the ability to walk one-quarter of a mile without assistance [OR 6.27, 95% CI 5.64-6.98; P<0.0001]) and more likely to be depressed (OR 1.78, 95% CI 1.60-1.99; P<0.0001) than their counterparts. On multivariate regression analysis adjusting for sociodemographic factors and health characteristics, only functional capacity remained an independent predictor of CHD (OR 1.81, 95% CI 1.42-2.31; P<0.0001).

CONCLUSION

Functional capacity was an independent predictor of CHD in the study population, whereas depression and sleep duration were not independent predictors.

摘要

目的

评估功能能力是否比抑郁或睡眠时长异常更能预测冠心病(CHD)。

方法

使用多阶段区域概率抽样,通过横断面家庭访谈调查,在美国招募成年平民(n=29818 人,平均年龄 48±18 岁,年龄范围 18-85 岁)。获得了慢性疾病、估计的习惯性睡眠时长、功能能力、抑郁情绪以及社会人口统计学特征的数据。

结果

35%的参与者报告功能能力下降。白人和黑人美国人的 CHD 发生率分别为 5.2%和 4%。患有 CHD 的人更有可能报告极端的睡眠时长(短睡眠[≤5 小时]或长睡眠[≥9 小时];比值比[OR]1.65,95%置信区间[CI]1.38-1.97;P<0.0001),不太可能具有功能性活动(以无需帮助行走四分之一英里的能力为基准[OR 6.27,95% CI 5.64-6.98;P<0.0001]),更有可能抑郁(OR 1.78,95% CI 1.60-1.99;P<0.0001),而不是他们的同龄人。在调整社会人口统计学因素和健康特征的多变量回归分析中,只有功能能力仍然是 CHD 的独立预测因素(OR 1.81,95% CI 1.42-2.31;P<0.0001)。

结论

在研究人群中,功能能力是 CHD 的独立预测因素,而抑郁和睡眠时长不是独立预测因素。

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