Brooklyn Health Disparities Center, Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY 11203-2098, USA.
Sleep Med. 2012 Jun;13(6):728-31. doi: 10.1016/j.sleep.2012.01.015. Epub 2012 Mar 31.
To assess whether functional capacity is a better predictor of coronary heart disease (CHD) than depression or abnormal sleep duration.
Adult civilians in the USA (n=29,818, mean age 48 ± 18 years, range 18-85 years) were recruited by a cross-sectional household interview survey using multistage area probability sampling. Data on chronic conditions, estimated habitual sleep duration, functional capacity, depressed moods, and sociodemographic characteristics were obtained.
Thirty-five percent of participants reported reduced functional capacity. The CHD rates among White and Black Americans were 5.2% and 4%, respectively. Individuals with CHD were more likely to report extreme sleep durations (short sleep [≤ 5h] or long sleep [≥ 9 h]; odds ratio [OR] 1.65, 95% confidence interval [CI] 1.38-1.97; P<0.0001), less likely to be functionally active (anchored by the ability to walk one-quarter of a mile without assistance [OR 6.27, 95% CI 5.64-6.98; P<0.0001]) and more likely to be depressed (OR 1.78, 95% CI 1.60-1.99; P<0.0001) than their counterparts. On multivariate regression analysis adjusting for sociodemographic factors and health characteristics, only functional capacity remained an independent predictor of CHD (OR 1.81, 95% CI 1.42-2.31; P<0.0001).
Functional capacity was an independent predictor of CHD in the study population, whereas depression and sleep duration were not independent predictors.
评估功能能力是否比抑郁或睡眠时长异常更能预测冠心病(CHD)。
使用多阶段区域概率抽样,通过横断面家庭访谈调查,在美国招募成年平民(n=29818 人,平均年龄 48±18 岁,年龄范围 18-85 岁)。获得了慢性疾病、估计的习惯性睡眠时长、功能能力、抑郁情绪以及社会人口统计学特征的数据。
35%的参与者报告功能能力下降。白人和黑人美国人的 CHD 发生率分别为 5.2%和 4%。患有 CHD 的人更有可能报告极端的睡眠时长(短睡眠[≤5 小时]或长睡眠[≥9 小时];比值比[OR]1.65,95%置信区间[CI]1.38-1.97;P<0.0001),不太可能具有功能性活动(以无需帮助行走四分之一英里的能力为基准[OR 6.27,95% CI 5.64-6.98;P<0.0001]),更有可能抑郁(OR 1.78,95% CI 1.60-1.99;P<0.0001),而不是他们的同龄人。在调整社会人口统计学因素和健康特征的多变量回归分析中,只有功能能力仍然是 CHD 的独立预测因素(OR 1.81,95% CI 1.42-2.31;P<0.0001)。
在研究人群中,功能能力是 CHD 的独立预测因素,而抑郁和睡眠时长不是独立预测因素。