Peng Yan, Peng Fen, Yi Shou-Xiang, Lin Ya-Ping, Chang Xiao-Rong, Long Yi-Wen, Zhang Hong-Guo
College of Acupuncture-Moxibustion and Massage, Hunan University of TCM, Major Laboratory of Meridians and Viscera, Tertiary Laboratory of State Administration of TCM, Changsha 410007, China.
Zhongguo Zhen Jiu. 2012 Mar;32(3):246-50.
To explore the mechanism of reinforcing function of moxibustion to spleen-stomach.
Forty healthy Sprague Dawley rats were randomly divided into 4 groups: group A (blank group), group B (model group), group C (moxibustion group) and group D (herbs group). The rat model of spleen-deficiency was established by intragastric administration with 200% Dahuang (Rhubarb) infusion. The rats in group A and B, and D served as the blank control, model, and Sijunzi decoction group respectively, while those in group C received moxibustion at "Zusanli" (ST 36), "Zhongwan" (CV 12), "Guanyuan" (CV 4), "Pishu" (BL 20) and "Weishu" (BL 21), etc. The common symptoms and intestinal propulsive rate were observed. The content of I-xylose in serum was detected by phloroglucinol method. Colorimetry method was used to detected content of ATP in jejunum tissues.
Compared with group A, the symptom score in group B was increased significantly (both P < 0.01), while the intestinal propulsive rates, the content of D-xylose in serum and ATP in jejunum tissues were decreased significantly (P < 0.05, P < 0.01). Compared with group B, the symptom score in group C and D was decreased significantly (both P < 0.01), while the intestinal propulsive rates, the content of D-xylose in serum and ATP in jejunum tissues were increased significantly (P < 0.05, P < 0.01). There were no significant difference between group C and D (P > 0.05).
Moxibustion at "Zusanli" (ST 36) etc. could relieve symptoms of spleen-deficiency, enhance motility and absorption functions of small intestine and improve metabolism of small intestine. The efficacy is equal to administration of Sijunzi decoction.
探讨艾灸对脾胃的补益作用机制。
将40只健康的SD大鼠随机分为4组：A组（空白组）、B组（模型组）、C组（艾灸组）和D组（中药组）。采用200%大黄水煎液灌胃建立脾虚大鼠模型。A组和B组、D组大鼠分别作为空白对照、模型、四君子汤组，C组大鼠于“足三里”（ST 36）、“中脘”（CV 12）、“关元”（CV 4）、“脾俞”（BL 20）、“胃俞”（BL 21）等穴位进行艾灸。观察一般症状及小肠推进率。采用间苯三酚法检测血清中D-木糖含量。采用比色法检测空肠组织中ATP含量。
与A组比较，B组症状评分显著升高（均P < 0.01），而小肠推进率、血清中D-木糖含量及空肠组织中ATP含量显著降低（P < 0.05，P < 0.01）。与B组比较，C组和D组症状评分显著降低（均P < 0.01），而小肠推进率、血清中D-木糖含量及空肠组织中ATP含量显著升高（P < 0.05，P < 0.01）。C组与D组比较差异无统计学意义（P > 0.05）。
艾灸“足三里”等穴位可缓解脾虚症状，增强小肠运动及吸收功能，改善小肠代谢。其疗效与四君子汤相当。
