Khan Haris M, Shujatullah Fatima, Shahid M, Raza Adil, Malik Ritu
Dept. of Microbiology, J.N. Medical College, Aligarh, UP.
J Commun Dis. 2010 Jun;42(2):153-6.
Malaria is one of the most common parasitic infection in India. The diagnosis largely depends on peripheral blood smear examination. Newer diagnostic methods like various antigen detection assays are now in use for prompt diagnosis and treatment. This study was done to determine the effectiveness of Diagnos Malaria Stix (antigen detection) assay in diagnosis of malaria. This involves detection of PfHRP-2 antigen and P.V. specific pLDH antigen. 162 patients with signs and symptoms of malaria included in the study. Leishman stained blood smear examination was done for all patients. Commercially available Diagnos Malaria Stix assay was used. Diagnos Malaria Stix showed sensitivity, specificity positive and negative predictive values of 100% each while Sensitivity, specificity, positive and negative predictive values of Leishman stained blood smear examination were 45.45%, 100%, 100% and 92% respectively.
疟疾是印度最常见的寄生虫感染之一。诊断很大程度上依赖于外周血涂片检查。各种抗原检测分析等更新的诊断方法目前用于快速诊断和治疗。本研究旨在确定诊断疟疾试纸条（抗原检测）分析在疟疾诊断中的有效性。这涉及检测PfHRP - 2抗原和间日疟原虫特异性pLDH抗原。162名有疟疾症状和体征的患者纳入研究。对所有患者进行利什曼染色血涂片检查。使用市售的诊断疟疾试纸条分析。诊断疟疾试纸条的敏感性、特异性、阳性和阴性预测值均为100%，而利什曼染色血涂片检查的敏感性、特异性、阳性和阴性预测值分别为45.45%、100%、100%和92%。
