Christchurch Health and Development Study, Department of Psychological Medicine, University of Otago, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand.
Drug Alcohol Depend. 2012 Oct 1;125(3):295-300. doi: 10.1016/j.drugalcdep.2012.03.003. Epub 2012 Apr 1.
This study examined the associations between the transition to parenthood and substance use disorders from ages 18 to 30 in a New Zealand birth cohort.
Outcomes included: DSM-IV criteria for: (a) alcohol abuse/dependence (AAD) and (b) illicit substance abuse/dependence. The study also used measures transition to parenthood during the period 18-30 years; and observed covariate factors including: family socio-economic status; family functioning; childhood abuse exposure; childhood personal and behavioural characteristics; and psychosocial adjustment in adolescence. Data were analysed using repeated measures generalised estimating equation models, and conditional fixed effects regression modelling to control for confounding. Gender interactions were examined using moderated regression analyses.
Those who became parents had unadjusted odds of substance use disorder outcomes that were approximately 50% lower than those who had not become parents. Adjustment of the associations for both: (a) observed confounding factors and (b) non-observed fixed effects; strengthened the associations between parenthood status and substance use disorders. Custodial parents had odds of substance use disorders that were 57-78% lower than those who did not become parents after adjusting for non-observed fixed effects. Additional analyses suggested these effects were confined to custodial parents only. There was also evidence for gender×parenthood status interactions for AAD, with the effects of parenthood on AAD being stronger for females.
The results suggest that the transition to custodial parenthood may result in reduced risks of substance use disorder, particularly amongst female cohort members.
本研究在新西兰出生队列中,从 18 岁到 30 岁的年龄,研究了成为父母与物质使用障碍之间的关联。
研究结果包括:DSM-IV 标准的:(a)酒精滥用/依赖(AAD)和(b)非法物质滥用/依赖。该研究还使用了在 18-30 岁期间过渡到父母身份的措施;并观察了包括家庭社会经济地位;家庭功能;儿童期虐待暴露;儿童期个人和行为特征;以及青春期的心理社会适应等观察性协变量。使用重复测量广义估计方程模型和条件固定效应回归模型分析数据,以控制混杂因素。使用调节回归分析检验性别交互作用。
与未成为父母的人相比,成为父母的人未经调整的物质使用障碍结果的几率降低了约 50%。调整以下两种情况的关联:(a)观察到的混杂因素和(b)未观察到的固定效应;加强了父母身份与物质使用障碍之间的关联。与未成为父母的人相比,监护父母的物质使用障碍的几率在调整未观察到的固定效应后降低了 57-78%。进一步的分析表明,这些影响仅局限于监护父母。对于 AAD,也有性别×父母身份状态交互作用的证据,父母身份对 AAD 的影响对于女性更强。
研究结果表明,过渡到监护父母身份可能会降低物质使用障碍的风险,尤其是对于女性队列成员。