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Increased plasma levels of granzymes in adult patients with chronic immune thrombocytopenia.

作者信息

Olsson Bob, Jernås Margareta, Wadenvik Hans

出版信息

Thromb Haemost. 2012 Jun;107(6):1182-4. doi: 10.1160/TH12-01-0012. Epub 2012 Apr 4.

DOI:10.1160/TH12-01-0012
PMID:22476618
Abstract
摘要

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Emerging Concepts in Immune Thrombocytopenia.
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CD8(+) T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia.在免疫性血小板减少症中，CD8(+) T细胞通过使血小板去唾液酸化诱导肝脏中的血小板清除。
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Interleukin 27 inhibits cytotoxic T-lymphocyte-mediated platelet destruction in primary immune thrombocytopenia.白细胞介素27抑制原发性免疫性血小板减少症中细胞毒性T淋巴细胞介导的血小板破坏。
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