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[作为重要生物材料的唾液中乙醇水平的测定]

[Determination of levels of ethyl alcohol in saliva as an important biological material].

作者信息

Urbanský A

机构信息

Ustav súdneho lekárstva, Kosice.

出版信息

Soud Lek. 1990 Aug;35(3):33-8.

PMID:2247783
Abstract

Saliva can be suitable biological material for assessment of the ethanol level, in particular in those subjects who for various reasons refuse to have blood samples taken. This statement is based on the results of a trail in 123 subjects. Probands were given alcoholic beverages in amounts that the ethanol level--with regard to the danger of intolerance--if possible did not exceed 1.5 g.kg-1 in the blood stream. Approximately 90 mins. after ingestion of the alcoholic beverage, i.e. during the postabsorptive stage blood and saliva specimens were collected assessment of the ethanol level. Comparison of ethanol levels in blood and saliva revealed in 78 subjects identical levels. In 40 subjects there was a difference of +/- 0.1 g.kg-1 and only in five subjects ther was a difference of +/- 0.2 g.kg-1. These differences can be considered negligible with regard to hitherto used estimates of the ethanol level in other biological materials. From the experiment it is also apparent that the ethanol level does not change substantially when saliva is stored for periods up to 6 days when the final examination be mode.

摘要

唾液可能是用于评估乙醇水平的合适生物材料,特别是对于那些因各种原因拒绝采集血样的受试者。这一说法基于对123名受试者的一项试验结果。先证者饮用酒精饮料的量,就不耐受风险而言,尽可能使血流中的乙醇水平不超过1.5 g·kg-1。在摄入酒精饮料约90分钟后,即在吸收后阶段采集血液和唾液样本以评估乙醇水平。血液和唾液中乙醇水平的比较显示,78名受试者的水平相同。40名受试者的差异为±0.1 g·kg-1,只有5名受试者的差异为±0.2 g·kg-1。就迄今用于估计其他生物材料中乙醇水平的方法而言,这些差异可忽略不计。从实验中还可以明显看出,当唾液储存长达6天进行最终检测时,乙醇水平基本不变。

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2
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