Morpurgo F G, Hack W W, Ree E F, Weyers T, van der Harten J J, Taets van Amerongen A
Afdelingen Kindergeneeskunde, Academisch Ziekenhuis Vrije Universiteit, Amsterdam.
Tijdschr Kindergeneeskd. 1990 Oct;58(5):179-82.
A male neonate born after spontaneous labor during the 25 3/7 week of gestation, developed a fatal course of disseminated candidiasis. Disseminated candidiasis is seen in newborns undergoing intensive care and has a high mortality rate. Important etiologic factors are low immunologic response, invasive monitoring techniques, systemic antibiotics and parenteral nutrition. Early diagnosis and efficient antimycotic therapy with amphotericin B and if necessary combined with flucytosine contribute a great deal to the chance of survival.
一名在妊娠25又3/7周时自然分娩的男婴，患上了播散性念珠菌病并最终死亡。播散性念珠菌病在接受重症监护的新生儿中较为常见，死亡率很高。重要的病因包括免疫反应低下、侵入性监测技术、全身性抗生素使用和肠外营养。早期诊断以及使用两性霉素B进行有效的抗真菌治疗，必要时联合氟胞嘧啶，对提高存活率有很大帮助。
