Tajtáková M, Farkasová E, Klubertová M, Konrádová I, Machovcáková L
Katedra internej medicíny 1 LF UPJS, Kosice.
Vnitr Lek. 1990 Jul;36(7):649-53.
The authors investigated the age of onset of the menopause by random selection, using a questionnaire, in 344 women aged 43 to 90 years in relation to smoking. They evaluated 107 non-smokers, 112 passive smokers, and 118 active smokers. The mean age of onset of the menopause in non-smokers was 49.8 +/- 4.1, in passive smokers 49.1 +/- 4.9 and in active smokers 48.1 +/- 4.3 years. Active smokers had their menopause on average by 1.7 years sooner than non-smokers (p less than 0.01). This difference depended on the duration of smoking and increased with the number of smoked cigarettes to as much as 2.4 years in smokers of greater than 20 cigarettes per day and to three years when also the mother of the investigated woman was a smoker (p less than 0.01).
作者通过随机抽样，采用问卷调查的方式，对344名年龄在43岁至90岁之间的女性进行了绝经年龄与吸烟关系的调查。他们评估了107名非吸烟者、112名被动吸烟者和118名主动吸烟者。非吸烟者绝经的平均年龄为49.8±4.1岁，被动吸烟者为49.1±4.9岁，主动吸烟者为48.1±4.3岁。主动吸烟者绝经的平均年龄比非吸烟者早1.7年（p<0.01）。这种差异取决于吸烟的持续时间，并且随着每天吸烟量的增加而增大，对于每天吸烟超过20支的吸烟者，这种差异高达2.4年；当被调查女性的母亲也是吸烟者时，差异则高达3年（p<0.01）。
