Marks R, Dykes P J
Department of Medicine, University of Wales, College of Medicine, Cardiff, United Kingdom.
Wien Med Wochenschr Suppl. 1990;108:16-8.
Detergent substances are important components of cleansing materials. Their detergent cleansing action may also result in skin toxicity. Methods for the evaluation of their toxic effect on the skin surface are reviewed stressing the usefulness of the soap chamber test, and newer in vitro cultural techniques. The action of detergents in promoting desquamation and removing intercorneocyte materials is also discussed. Finally, the point is made that cleansing can also be accomplished with non-detergent containing cleaners.
洗涤剂物质是清洁材料的重要组成部分。它们的洗涤清洁作用也可能导致皮肤毒性。本文综述了评估其对皮肤表面毒性作用的方法，强调了肥皂腔试验和更新的体外培养技术的实用性。还讨论了洗涤剂在促进脱屑和去除角质形成细胞间物质方面的作用。最后指出，不含洗涤剂的清洁剂也可以实现清洁。
