受阻塞性睡眠呼吸暂停影响的医学病症。

Medical disorders impacted by obstructive sleep apnea.

作者信息

Bista Sabin R, Barkoukis Teri J

机构信息

Division of Pulmonary, Critical Care, Sleep and Allergy, University of Nebraska Medical Center, Nebraska Medical Center, Omaha, NE 68198-5300, USA.

出版信息

Dent Clin North Am. 2012 Apr;56(2):373-86. doi: 10.1016/j.cden.2012.01.002.

DOI:10.1016/j.cden.2012.01.002

PMID:22480809

Abstract

Normal-sleeping individuals experience a lower metabolic rate and relative cardiovascular quiescent state with lower heart rate and blood pressure that naturally occurs during sleep compared with the waking state. In patients with obstructive sleep apnea (OSA), this quiescent state becomes disrupted. Research has shown a higher risk for several medical disorders, most ominous being a myocardial infarction or stroke. This article serves as an overview to the cardiovascular, cerebrovascular, metabolic, and gastroesophageal effects of OSA.

摘要

正常睡眠的个体与清醒状态相比，在睡眠期间会经历较低的代谢率以及相对的心血管静止状态，此时心率和血压较低，这是睡眠中自然发生的。在阻塞性睡眠呼吸暂停（OSA）患者中，这种静止状态会被打乱。研究表明，患几种医学疾病的风险更高，最严重的是心肌梗死或中风。本文概述了OSA对心血管、脑血管、代谢和胃食管的影响。