Dipartimento di Biotecnologie e Bioscienze, Università di Milano-Bicocca, Milan, Italy.
Chem Soc Rev. 2012 Jun 7;41(11):4306-34. doi: 10.1039/c2cs15337h. Epub 2012 Apr 5.
In this review an overview about biological applications of magnetic colloidal nanoparticles will be given, which comprises their synthesis, characterization, and in vitro and in vivo applications. The potential future role of magnetic nanoparticles compared to other functional nanoparticles will be discussed by highlighting the possibility of integration with other nanostructures and with existing biotechnology as well as by pointing out the specific properties of magnetic colloids. Current limitations in the fabrication process and issues related with the outcome of the particles in the body will be also pointed out in order to address the remaining challenges for an extended application of magnetic nanoparticles in medicine.
在这篇综述中，将概述磁性胶体纳米粒子的生物学应用，包括它们的合成、表征以及体外和体内应用。通过强调与其他纳米结构和现有生物技术的集成可能性以及指出磁性胶体的特殊性质，来讨论与其他功能纳米粒子相比，磁性纳米粒子的潜在未来作用。还将指出在制造过程中的当前局限性以及与粒子在体内的结果相关的问题，以解决在医学中广泛应用磁性纳米粒子的剩余挑战。
