Urology Department, Peking University People's Hospital, Beijing, China.
Urology. 2012 Jun;79(6):1385-8. doi: 10.1016/j.urology.2011.11.091. Epub 2012 Apr 5.
To tentatively evaluate the usefulness of self-management interventions in improving the lower urinary tract symptoms (LUTS) and quality of life (QoL) in patients with benign prostatic hyperplasia (BPH).
Two-hundred twent-two men were recruited from a teaching hospital at Peking University from March 2008 to September 2009. They were referred by general practitioners to urologic outpatient departments because of BPH after 3-month administration of α-blockers. Participants were randomized to attend either a self-management program or undergo standard care. Difference of scores of International Prostate Symptom Score (IPSS) and BPH-specific QoL scale between 2 groups was analyzed at the enrollment period, and at the first week, third month, and sixth month.
All participants had been followed for 6 months. There was no significant difference in IPSS score and QoL score between the 2 groups at the enrollment period and first week, whereas at the third month and sixth month, the IPSS scores and QoL self-management interventional group scores were statistically significant lower than those of the standard care group.
Self-management intervention may be associated with decreased LUTS symptoms and may improve QoL in BPH patients with α-blocker administration.
初步评估自我管理干预在改善良性前列腺增生(BPH)患者下尿路症状(LUTS)和生活质量(QoL)方面的作用。
2008 年 3 月至 2009 年 9 月,我们从北京大学的一家教学医院招募了 222 名男性。他们因 BPH 在接受 3 个月的α受体阻滞剂治疗后,经全科医生转诊至泌尿科门诊。参与者被随机分配参加自我管理计划或接受标准护理。在入组期、第 1 周、第 3 个月和第 6 个月,分析 2 组间国际前列腺症状评分(IPSS)和 BPH 特异性生活质量评分的差异。
所有参与者均随访 6 个月。入组期和第 1 周时,2 组的 IPSS 评分和 QoL 评分无显著差异,而在第 3 个月和第 6 个月时,自我管理干预组的 IPSS 评分和 QoL 评分明显低于标准护理组。
自我管理干预可能与减轻 LUTS 症状有关,并可能改善接受α受体阻滞剂治疗的 BPH 患者的生活质量。