Magnetic Resonance and Image Analysis Research Centre (MARIARC), University of Liverpool, UK.
Brain Lang. 2012 Jun;121(3):206-18. doi: 10.1016/j.bandl.2012.03.003. Epub 2012 Apr 5.
We investigated the effect of handedness and sex on: (i) sulcal contours defining PO and PTR and (ii) volume estimates of PO and PTR subfields in 40 left- and 42 right-handers. Results show an effect of handedness on discontinuity of the inferior frontal sulcus (IFS: P<0.01). Discontinuity of IFS was observed in: 43% left- and 62% right hemispheres in right-handers and in 65% left- and 48% right-hemispheres in left-handers. PO volume asymmetry was rightward in left-handed males (P=0.007) and females (P=0.02), showed a leftward trend in right-handed males (P=0.06), and was non-asymmetrical in right-handed females (P=0.96, i.e. left- and right-hemisphere PO volumes did not differ significantly). PO volume asymmetry in males differed significantly between handedness groups (P=0.001). Findings indicate a high degree of variability in the sulcal contours of PO and PTR and volume asymmetry of PO: the factors sex and handedness can explain some of this variability.
（i）定义 PO 和 PTR 的脑沟轮廓；（ii）PO 和 PTR 子区的体积估计。结果显示利手对额下回（IFS）不连续性有影响（P<0.01）。IFS 的不连续性在右利手者中观察到 43%的左侧和 62%的右侧半球，在左利手者中观察到 65%的左侧和 48%的右侧半球。左侧男性（P=0.007）和女性（P=0.02）的 PO 体积不对称性偏向右侧，右侧男性（P=0.06）表现出左偏趋势，右侧女性（P=0.96，即左侧和右侧 PO 体积无显著差异）无不对称性。男性的 PO 体积不对称性在手性组之间有显著差异（P=0.001）。研究结果表明，PO 和 PTR 的脑沟轮廓以及 PO 的体积不对称性具有高度的可变性：性别和利手等因素可以解释其中的一些可变性。
