促肾上腺皮质激素对多发性硬化症患者某些粒细胞蛋白酶活性的影响。
Influence of ACTH on activity of some granulocytic proteases in patients with multiple sclerosis.
作者信息
Czernicki J, Tchórzewski H, Chmielewski H
出版信息
Arch Immunol Ther Exp (Warsz). 1979;27(3):345-9.
PMID:224833
Abstract
The effect of treatment with ACTH on activity of granulocytic acid and neutral proteases in patients suffering from multiple sclerosis was studied. Protease activity was distinctly higher in granulocytes from patients. ACTH normalized the activities investigated in patients with exacerbating course multiple sclerosis, but had no influence on hydrolases in the progressive form of the disease.
摘要
研究了促肾上腺皮质激素（ACTH）治疗对多发性硬化症患者粒细胞酸性和中性蛋白酶活性的影响。患者粒细胞中的蛋白酶活性明显更高。ACTH使病情加重型多发性硬化症患者的所研究活性恢复正常，但对疾病进展型患者的水解酶没有影响。
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