Czernicki J, Chmielewski H
Neurol Neurochir Pol. 1978 Jan-Feb;12(1):29-33.
The activity of acid phosphatase, acid and neutral proteases in the serum, white blood cells and lysosomal granules and in the supernatant of the lysosomal fraction of peripheral blood granulocytes was determined in 33 patients with multiple sclerosis. The control group included 20 clinically unaffected subjects. A rise in the activity of neutral proteases in white blood cells was demonstrated at the time of multiple sclerosis exacerbations and a fall in the activity of these enzymes in lysosomal granules with its simultaneous rise in the supernatant of the lysosomal fraction of granulocytes was observed.
对33例多发性硬化症患者的血清、白细胞、溶酶体颗粒以及外周血粒细胞溶酶体部分的上清液中的酸性磷酸酶、酸性和中性蛋白酶活性进行了测定。对照组包括20名临床无症状的受试者。结果显示，在多发性硬化症发作时，白细胞中中性蛋白酶的活性升高，而溶酶体颗粒中这些酶的活性下降，同时粒细胞溶酶体部分的上清液中其活性升高。
