Riekkinen P, Palo J, Asikainen I
Acta Neurol Scand. 1977 Jul;56(1):83-6. doi: 10.1111/j.1600-0404.1977.tb01412.x.
The activities of three lysosomal enzymes were measured from the lymphocytes and granulocytes of patients with multiple sclerosis and of controls. The activity of acid phosphatase was increased in the granulocytes and that of beta-glucuronidase in the lymphocytes of MS patients in remission, as compared to those in relapse. No marked increases were observed in the activity of acid proteinase. These findings suggest that a number of lysosomal enzymes in both lymphocytes and granulocytes can be activated during demyelinating processes for reasons unknown at the moment.
对多发性硬化症患者及对照者的淋巴细胞和粒细胞中的三种溶酶体酶活性进行了测定。与疾病复发期相比，缓解期多发性硬化症患者粒细胞中的酸性磷酸酶活性增加，淋巴细胞中的β-葡萄糖醛酸酶活性增加。酸性蛋白酶活性未观察到明显增加。这些发现表明，淋巴细胞和粒细胞中的一些溶酶体酶在脱髓鞘过程中可能因目前未知的原因而被激活。
