Department of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, Gagarin 7 Street, 87-100 Torun, Poland.
Talanta. 2012 May 15;93:117-21. doi: 10.1016/j.talanta.2012.01.057. Epub 2012 Feb 2.
Extraction techniques for 4,4'-methylenebis(2-chloroaniline) (MOCA) in air samples and water solutions were developed and compared. Classic techniques for air sampling of MOCA were enhanced by incorporating a derivatization step (3,5-dinitrobenzoyl chloride solution in toluene), thus increasing the limit of detection and limit of quantification. Sampling of MOCA from water solution was performed using novel nanoporous polymeric (polypyrrole and polythiophene) fiber coatings and solid phase microextraction. Samples were analyzed by high-performance liquid chromatography coupled with a UV detector. Using the modified method for air sampling of MOCA, we found that the limit of detection was 7.90 ng m(-3) and the limit of quantification was 23.8 ng m(-3). In contrast, the limit of detection for MOCA in water samples was 11.26 ng mL(-1) (polypyrrole) and 84.62 ng mL(-1) (polythiophene) and the limit of quantification for MOCA was from 33.78 (polypyrrole) and 253.86 ng mL(-1) (polythiophene). Correlation coefficients were 0.9997 for air and 0.8790-0.9852 for water samples, respectively. The techniques presented provide alternative methods for the determination of MOCA in air samples and in water solutions that are more sensitive, quicker and less expensive than previously established procedures.
开发并比较了用于空气中 4,4'-亚甲基双(2-氯苯胺)(MOCA)和水溶液中 MOCA 的提取技术。通过引入衍生化步骤(甲苯中的 3,5-二硝基苯甲酰氯溶液)，改进了 MOCA 的经典空气采样技术，从而提高了检测限和定量限。采用新型纳米多孔聚合物(聚吡咯和聚噻吩)纤维涂层和固相微萃取法从水溶液中采样 MOCA。通过高效液相色谱法与紫外检测器进行分析。使用改良的 MOCA 空气采样方法，我们发现检测限为 7.90ng/m³，定量限为 23.8ng/m³。相比之下，MOCA 在水样中的检测限为 11.26ng/mL(聚吡咯)和 84.62ng/mL(聚噻吩)，定量限为 33.78ng/mL(聚吡咯)和 253.86ng/mL(聚噻吩)。空气和水样的相关系数分别为 0.9997 和 0.8790-0.9852。所提出的技术为空气中和水溶液中 MOCA 的测定提供了替代方法，与先前建立的程序相比，这些方法更灵敏、更快且更经济。
