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胰腺淋巴上皮囊肿与 HIV 感染的关系。

Association between lymphoepithelial cysts of the pancreas and HIV infection.

机构信息

Department of Surgery, Division of Visceral Surgery, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil, 4, 1211 Geneva 14, Switzerland.

出版信息

Pancreatology. 2012 Jan-Feb;12(1):61-4. doi: 10.1016/j.pan.2011.12.002. Epub 2011 Dec 8.

DOI:10.1016/j.pan.2011.12.002
PMID:22487477
Abstract

BACKGROUND & AIMS: To report the association of lymphoepithelial cysts (LEC) of the pancreas with Human Immunodeficiency Virus (HIV) infection. An association between LEC and HIV infection is already established in the parotid gland (PG).

METHODS

Report of the first two cases of LEC of the pancreas associated with HIV infection and comparison of the clinical and histopathological aspects of LECs of the pancreas and of the PG.

RESULTS

LECs of the pancreas were discovered by CT imaging in 2 patients with a history of HIV infection. Notably, LEC completely resolved in one patient after initiation of antiretroviral therapy.

CONCLUSION

This is the first report of an association of LEC of the pancreas and HIV infection. In the presence of LEC of the pancreas, we propose a systematic screening for HIV infection and associated lesions in the PG. Antiretroviral therapy should be initiated in untreated patients. Surgery should be reserved for symptomatic patients in whom medical therapy has failed.

摘要

背景与目的

报告胰腺淋巴上皮囊肿(LEC)与人类免疫缺陷病毒(HIV)感染之间的关联。PG 中 LEC 和 HIV 感染之间的关联已经确立。

方法

报告首例与 HIV 感染相关的胰腺 LEC 病例,并比较胰腺和 PG 中 LEC 的临床和组织病理学特征。

结果

2 例 HIV 感染史患者通过 CT 成像发现胰腺 LEC。值得注意的是,一名患者开始抗逆转录病毒治疗后 LEC 完全消退。

结论

这是胰腺 LEC 与 HIV 感染相关的首例报告。在存在胰腺 LEC 的情况下,我们建议对 HIV 感染和 PG 中的相关病变进行系统筛查。应在未治疗的患者中启动抗逆转录病毒治疗。对于药物治疗失败的有症状患者,应保留手术治疗。

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