Román F, Toldi Z, Kürti K, Pataki L
Children's Hospital, Szeged, Hungary.
Acta Paediatr Hung. 1990;30(2):233-9.
The sodium and potassium concentrations of the red blood cells and the serum were investigated in 21 children with diabetes mellitus. Measurements were made prior to and 1 and 2 hours following insulin administration. Before insulin treatment, the sodium level in the red blood cells of the diabetes patients was significantly higher that the control level, while the potassium level was significantly depressed. These differences were not observed 1 and 2 hours following insulin administration. Attention is drawn to the rapid and extensive electrolyte changes in the red blood cells of diabetics in response to insulin. The potassium content of the serum of the diabetics was significantly decreased by insulin administration. No correlation was found between the electrolyte levels and the fasting blood glucose levels. A weak negative correlation (p less than 0.02) was observed between the potassium content of the red blood cells and the duration of the illness. The pathogenetic, diagnostic and therapeutic implications of the results are discussed.
对21名糖尿病患儿的红细胞和血清中的钠、钾浓度进行了研究。在注射胰岛素之前以及注射后1小时和2小时进行了测量。在胰岛素治疗前，糖尿病患者红细胞中的钠水平显著高于对照水平，而钾水平则显著降低。在注射胰岛素后1小时和2小时未观察到这些差异。需注意糖尿病患者红细胞中电解质会因胰岛素而发生快速而广泛的变化。注射胰岛素后糖尿病患者血清中的钾含量显著降低。未发现电解质水平与空腹血糖水平之间存在相关性。观察到红细胞中的钾含量与病程之间存在弱负相关（p小于0.02）。讨论了这些结果在发病机制、诊断和治疗方面的意义。
