Guthrie J W, Keeley B J, Maddock E, Bright S R, May C
Northwest Surgeons, Delamere House, Ashville Point, Sutton Weaver, Cheshire WA7 3FW.
J Small Anim Pract. 2012 May;53(5):273-7. doi: 10.1111/j.1748-5827.2011.01202.x. Epub 2012 Apr 10.
To determine the effect of signalment on the incidence and presentation of patients suffering from cranial cruciate ligament disease.
Data relating to 426 dogs (44 breeds) that met specific selection criteria were obtained from the hospital archive (2002 to 2008). Cases were followed up for 2 years.
The breeds most commonly presented with cranial cruciate ligament disease were Labrador retriever (16%), Rottweiler (15%), golden retriever (12%) and boxer (9%). Rottweilers were significantly more likely (69%; P=0·05) to develop and present with (50%; P=0·03) bilateral cranial cruciate ligament disease. Rottweilers presenting with cranial cruciate ligament disease were significantly younger (median 977 days; P<0·0001) than other breeds; golden retrievers being significantly older at presentation (median 1994 days; P=0·004). Neither sex nor neutered status significantly affected the incidence of developing (P=0·77 and P=0·30, respectively) or presenting with (P=0·62 and P=0·35, respectively) bilateral cranial cruciate ligament disease. Entire dogs were significantly younger than neutered dogs at presentation (P=0·0004). Entire female dogs presented significantly younger than neutered females (P=0·0002), entire males (P=0·01) and neutered males (P=0·0001).
Breed affects the incidence of developing and presenting with bilateral cranial cruciate ligament disease. Breed and sex both affect the age that patients present with cranial cruciate ligament disease.
确定品种特征对患有颅交叉韧带疾病患者的发病率及临床表现的影响。
从医院档案(2002年至2008年)中获取符合特定选择标准的426只犬(44个品种)的相关数据。对病例进行了2年的随访。
最常出现颅交叉韧带疾病的品种是拉布拉多寻回犬(16%)、罗威纳犬(15%)、金毛寻回犬(12%)和拳师犬(9%)。罗威纳犬发生双侧颅交叉韧带疾病的可能性显著更高(69%;P=0.05),且出现双侧疾病的比例也显著更高(50%;P=0.03)。患有颅交叉韧带疾病的罗威纳犬比其他品种明显更年轻(中位年龄977天;P<0.0001);金毛寻回犬发病时年龄明显更大(中位年龄1994天;P=0.004)。性别和绝育状态均未显著影响发生(分别为P=0.77和P=0.30)或出现(分别为P=0.62和P=0.35)双侧颅交叉韧带疾病的发病率。未绝育犬发病时比绝育犬明显更年轻(P=0.0004)。未绝育母犬发病时比绝育母犬(P= 0.0002)、未绝育公犬(P=0.01)和绝育公犬(P=0.0001)都明显更年轻。
品种影响双侧颅交叉韧带疾病的发生及出现比例。品种和性别均影响患者出现颅交叉韧带疾病的年龄。